Trial · NCT03575130
Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy
NCT03575130, Phase 2, Unknown, University of Erlangen-Nürnberg Medical School
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy. Trials, record NCT03575130. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03575130
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy
- NCT number
- NCT03575130
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 21 participants, estimated
- Lead sponsor
- University of Erlangen-Nürnberg Medical School
- Conditions
- Fuchs' Endothelial Dystrophy, Fuchs Dystrophy, Corneal Endothelial Dystrophy, Corneal Endothelial Cell Loss, Cornea Guttata
- Interventions
- Ripasudil eye drops, Optive eye drops, Descemetorhexis
- First posted
- 2018-07-02
- Last updated
- 2018-07-12
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The occurrence of serious adverse reaction within the observation period of 3 months after descemetorhexis. | 3 Months | |
| Secondary | rate of adverse event, adverse reaction, serious adverse event, serious adverse reaction and suspected unexpected serious adverse reaction | within the observation period of 6 months | |
| Secondary | effect of ripasudil on corneal endothelial cell density (ECD) | within the observation period of 6 months | |
| Secondary | effect of ripasudil on corneal thickness | within the observation period of 6 months | |
| Secondary | effect of on visual acuity (BCVA) | within the observation period of 6 months | |
| Secondary | effect of ripasudil on contrast sensitivity | within the observation period of 6 months | |
| Secondary | assess the need of rescue therapy (DMEK) | within the observation period of 6 months |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03575130
GET https://conductscience.org/api/trials/v1/NCT03575130/registered