Trial · NCT03593759
Cardiac Sarcoidosis Randomized Trial
NCT03593759, Phase 3, Recruiting, Ottawa Heart Institute Research Corporation
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cardiac Sarcoidosis Randomized Trial. Trials, record NCT03593759. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03593759
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cardiac Sarcoidosis Randomized Trial
- NCT number
- NCT03593759
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 160 participants, estimated
- Lead sponsor
- Ottawa Heart Institute Research Corporation
- Conditions
- Cardiac Sarcoidosis, Sarcoidosis
- Interventions
- Prednisone or Prednisolone, Methotrexate
- First posted
- 2018-07-20
- Last updated
- 2026-07-10
Source ClinicalTrials.gov
Registered outcomes20
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Summed perfusion rest score (SPRS) on FDG-PET scan | 6 months | Measure of myocardial scarring and fibrosis (blinded core lab analysis) |
| Secondary | Mortality | 6 months | All cause deaths |
| Secondary | Cardiovascular hospitalizations | 6 months | Cardiovascular related only |
| Secondary | Medication related adverse events | 6 months | Using clinical assessment, medication side-effect and adverse event reporting |
| Secondary | Modified Cleveland Clinic Glucocorticoid Toxicity Score | 6 months | Summed score of new/worsening diabetes;new/worsening HTN; osteoporosis; change in height and weight (combined and reported as BMI in kg/m2) |
| Secondary | Glucocorticoid Toxicity Index | 6 months | Composite scoring (improvement; no significant change; worsening) compared to baseline |
| Secondary | Patient reported symptoms related to medication | 6 months | Using medication side-effect questionnaire ( symptom present, yes or no; frequency; intensity) |
| Secondary | Medication compliance | 6 months | % of days where treatment was taken as prescribed |
| Secondary | Generic Quality of Life (SF 36) | 6 months | Measuring general QOL using SF-36 questionnaire |
| Secondary | Disease Specific Quality of Life (KSQ and SAT) | 6 months | Using Kings Sarcoidosis questionnaire and Sarcoidosis Assessment Tool |
1 to 10 of 20Source ClinicalTrials.gov
See all 20 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 31911261 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03593759
GET https://conductscience.org/api/trials/v1/NCT03593759/registered