Trial · NCT03595488
Dupilumab for Aspirin-exacerbated Respiratory Disease
NCT03595488, Phase 2, Completed, Rochester General Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dupilumab for Aspirin-exacerbated Respiratory Disease. Trials, record NCT03595488. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03595488
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dupilumab for Aspirin-exacerbated Respiratory Disease
- NCT number
- NCT03595488
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 11 participants, actual
- Lead sponsor
- Rochester General Hospital
- Conditions
- Aspirin-exacerbated Respiratory Disease
- Interventions
- Dupilumab
- First posted
- 2018-07-23
- Last updated
- 2020-08-26
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | SNOT 22 Score | From baseline to completion of study(7 months total) | This is a patient-reported outcome score for chronic rhinosinusitis with or without nasal polyposis |
| Secondary | UPSIT | From baseline to completion of study( 7 months total) | Univ. of Pennsylvania smell identification test |
| Secondary | Lund Mackay score | From baseline to completion of study( 7 months total) | Objective score for CT sinus imaging, this is a widely used method for radiologic staging of chronic rhinosinusitis. |
| Secondary | ACT score | From baseline to completion of study( 7 months total) | Validated asthma control test, a series of 5 questions related to patient's asthma control over the previous 4 weeks. |
| Secondary | Asthma Mini-AQLQ, 15 questions to assess quality of life. This assessment takes approximately 4-5 minutes to complete the questions. | From baseline to completion of study( 7 months total) | Validated asthma quality of life score |
| Secondary | Change in FEV1 | From baseline to completion of study( 7 months total) | Forced expiratory volume in first second from spirometry |
| Secondary | Change in FeNO | From baseline to completion of study( 7 months total) | Exhaled nitric oxide |
| Secondary | Eosinophil count | From baseline to completion of study( 7 months total) | Absolute eosinophil count |
| Secondary | Total serum IgE | From baseline to completion of study( 7 months total) | Total IgE |
| Secondary | Serum tryptase | From baseline to completion of study( 7 months total) | Biomarker |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers27
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03595488
GET https://conductscience.org/api/trials/v1/NCT03595488/papers?page=2