Trial · NCT03615651
Probiotic Effects on the Microbe-brain-gut Interaction and Brain Activity During Stress Tasks in Healthy Subjects
NCT03615651, Not applicable, Completed, Örebro University, Sweden
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Probiotic Effects on the Microbe-brain-gut Interaction and Brain Activity During Stress Tasks in Healthy Subjects. Trials, record NCT03615651. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03615651
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Probiotic Effects on the Microbe-brain-gut Interaction and Brain Activity During Stress Tasks in Healthy Subjects
- NCT number
- NCT03615651
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 22 participants, actual
- Lead sponsor
- Örebro University, Sweden
- Conditions
- Probiotics, Gut Microbiota, Emotional Stress, Magnetic Resonance Imaging
- Interventions
- Probiotic, Placebo
- First posted
- 2018-08-06
- Last updated
- 2018-08-06
Source ClinicalTrials.gov
Registered outcomes17
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in brain response to validated emotional challenge task (EAT) during functional brain imaging | Comparing week 4 and 12 | |
| Secondary | Change in brain response to a cognitive challenge task (MIST) during functional brain imaging | Comparing week 4 and 12 | |
| Other | Change in physical activity assessed by an actigraphy watch (actiwatch) | Comparing the change in week 0 compared to 4, and 8 compared to 12 (before and in the end of the two intervention periods) | Actigraph data regarding physical activity |
| Other | Change in sleep quality assessed by an actigraphy watch (actiwatch) | Comparing the change in week 0 compared to 4, and 8 compared to 12 (before and in the end of the two intervention periods) | Actigraph data regarding sleep quality |
| Other | Change in daily stress levels assessed by an actigraphy watch (actiwatch) | Comparing the change in week 0 compared to 4, and 8 compared to 12 (before and in the end of the two intervention periods) | Actigraph data regarding daily stress levels |
| Other | Autonomous Nervous System (ANS) Activity, Biopac | Comparing the change in week 0 compared to 4, and 8 compared to 12 (before and in the end of the two intervention periods) | ANS activity is measures during stressful tasks. |
| Other | Stroop test | Comparing the change in week 0 compared to 4, and 8 compared to 12 (before and in the end of the two intervention periods) | The Stroop test is performed for stress induction |
| Other | HADS (Hospital Anxiety and Depression Scale) | Measured weekly, week 1-12 | Hospital Anxiety and Depression Scale, min score 0, max score 3, total score max 42, subscale anxiety max 21, subscale depression max 21 |
| Other | STAI (State and Trait Anxiety Inventory for Adults) | Measured weekly, week 1-12 | State and Trait Anxiety Inventory for Adults |
| Other | PSS (Perceived Stress Scale) | Measured weekly, week 1-12 | Perceived Stress Scale, min score 0, max score 40 |
1 to 10 of 17Source ClinicalTrials.gov
See all 17 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 35571902 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| Stroop Color-Word Test | Other outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03615651
GET https://conductscience.org/api/trials/v1/NCT03615651/registered