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Trial · NCT03617536

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Weekly Mean of the Daily 24-hour Worst Itching Intensity Numerical Rating Scale (NRS) Score During Week 12CR845 0.25 mg Oral Tablet-3.9995% Confidence Interval -4.62 to -3.36score on a scale
Change From Baseline in Weekly Mean of the Daily 24-hour Worst Itching Intensity Numerical Rating Scale (NRS) Score During Week 12CR845 0.5 mg Oral Tablet-3.8495% Confidence Interval -4.50 to -3.18score on a scale
Change From Baseline in Weekly Mean of the Daily 24-hour Worst Itching Intensity Numerical Rating Scale (NRS) Score During Week 12CR845 1 mg Oral Tablet-4.4295% Confidence Interval -5.08 to -3.76score on a scale
Change From Baseline in Weekly Mean of the Daily 24-hour Worst Itching Intensity Numerical Rating Scale (NRS) Score During Week 12Placebo Oral Tablet-3.3295% Confidence Interval -3.97 to -2.68score on a scale
Change From Baseline in Total Skindex-10 Scale Score at the End of Week 12CR845 0.25 mg Oral Tablet-21.1995% Confidence Interval -24.34 to -18.04score on a scale
Change From Baseline in Total Skindex-10 Scale Score at the End of Week 12CR845 0.5 mg Oral Tablet-22.1395% Confidence Interval -25.37 to -18.89score on a scale
Change From Baseline in Total Skindex-10 Scale Score at the End of Week 12CR845 1 mg Oral Tablet-23.5795% Confidence Interval -27.00 to -20.14score on a scale
Change From Baseline in Total Skindex-10 Scale Score at the End of Week 12Placebo Oral Tablet-19.9595% Confidence Interval -23.17 to -16.73score on a scale
Change From Baseline in 5-D Itch Scale Score at the End of Week 12CR845 0.25 mg Oral Tablet-6.1795% Confidence Interval -7.10 to -5.25score on a scale
Change From Baseline in 5-D Itch Scale Score at the End of Week 12CR845 0.5 mg Oral Tablet-6.8495% Confidence Interval -7.78 to -5.90score on a scale
Change From Baseline in 5-D Itch Scale Score at the End of Week 12CR845 1 mg Oral Tablet-6.9795% Confidence Interval -7.97 to -5.97score on a scale
Change From Baseline in 5-D Itch Scale Score at the End of Week 12Placebo Oral Tablet-5.7495% Confidence Interval -6.69 to -4.80score on a scale
Reduction of Itch Intensity as Assessed by the Proportion of Patients Achieving an Improvement From Baseline ≥3 Points With Respect to the Weekly Mean of the Daily 24-hour Worst Itching Intensity NRS Score at Week 12
CR845 0.25 mg Oral Tablet66.295% Confidence Interval 53.00 to 77.32percentage of subjects
Reduction of Itch Intensity as Assessed by the Proportion of Patients Achieving an Improvement From Baseline ≥3 Points With Respect to the Weekly Mean of the Daily 24-hour Worst Itching Intensity NRS Score at Week 12
CR845 0.5 mg Oral Tablet64.895% Confidence Interval 51.18 to 76.30percentage of subjects
Reduction of Itch Intensity as Assessed by the Proportion of Patients Achieving an Improvement From Baseline ≥3 Points With Respect to the Weekly Mean of the Daily 24-hour Worst Itching Intensity NRS Score at Week 12
CR845 1 mg Oral Tablet72.195% Confidence Interval 58.62 to 82.45percentage of subjects
Reduction of Itch Intensity as Assessed by the Proportion of Patients Achieving an Improvement From Baseline ≥3 Points With Respect to the Weekly Mean of the Daily 24-hour Worst Itching Intensity NRS Score at Week 12
Placebo Oral Tablet57.995% Confidence Interval 44.15 to 70.49percentage of subjects

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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