Trial · NCT03624543
CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
NCT03624543, Phase 2, Active not recruiting, Canadian Cancer Trials Group
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. CFI-400945 in Patients With Advanced/Metastatic Breast Cancer. Trials, record NCT03624543. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03624543
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- CFI-400945 in Patients With Advanced/Metastatic Breast Cancer
- NCT number
- NCT03624543
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 51 participants, actual
- Lead sponsor
- Canadian Cancer Trials Group
- Conditions
- Breast Cancer
- Interventions
- CFI-400945
- First posted
- 2018-08-10
- Last updated
- 2026-09-16
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Objective Response defined by RECIST 1.1 | 2 years | |
| Secondary | Disease Control Rate (DCR) defined by RECIST 1.1 | 2 years | |
| Secondary | Number and severity of adverse events | 2 years | |
| Secondary | Molecular analyses of CFI-400945 on tumour cells through paired tumour biopsies using next generation DNA sequencing | 2 years | Molecular analyses including next-generation DNA sequencing will be performed on archival and recent tumour (or normal tissue) materials to identify potential biomarkers of response, histologically assess centrosomes and aberrant mitoses, and evaluate genomic alterations and other molecular features (i.e. gene or protein expression levels). |
| Secondary | Molecular analyses of CFI-400945 on tumour cells through paired biopsies using immunohistochemistry | 2 years | Assessment of centrosomes and aberrant mitoses and evaluation of genomic alterations and other molecular features (i.e. gene or protein expression levels) by molecular analyses including immunohistochemistry performed on archival and recent tumour (or normal tissue) materials to identify potential biomarkers of response. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03624543
GET https://conductscience.org/api/trials/v1/NCT03624543/registered