Trial · NCT03627611
Identification of Non-responders to Levothyroxine Therapy
NCT03627611, Phase 2, Completed, Oslo University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Identification of Non-responders to Levothyroxine Therapy. Trials, record NCT03627611. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03627611
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Identification of Non-responders to Levothyroxine Therapy
- NCT number
- NCT03627611
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 69 participants, actual
- Lead sponsor
- Oslo University Hospital
- Conditions
- Hypothyroidism, Biomarkers, Endocrine System Diseases
- Interventions
- Levothyroxin, Liothyronine
- First posted
- 2018-08-13
- Last updated
- 2021-03-17
- Other registries' IDs
- eudract:2017-003673-34
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Brown adipose tissue activation | 6 months | Thermal imaging of supraclavicular fossa |
| Secondary | Body temperature | 6 months | Rectal thermometer |
| Secondary | Energy expenditure | 6 months | Indirect calorimetry |
| Secondary | Muscle strength | 6 months | Hand grip test |
| Secondary | ThyPRO Questionnaire | 6 months | Thyroid patient reported outcome, 13 multi-item scale, range 0-100 with higher scores indicating poorer health status |
| Secondary | Mean levels of thyroid hormones | 6 months | TSH, free T4 and free T3 |
| Secondary | SF-36 Questionnaire | 6 months | Short form health survey, 8 multi-item scale, range 0-100 with higher scores indicating better health status |
| Secondary | Fatigue Questionnaire | 6 months | 11 item, range 0-33 with higher scores implying higher levels of fatigue |
| Secondary | New biomarkers | 6 months | Bone marrow fat, serum and urine |
| Secondary | Micro-RNA, miR-92a | 6 months | Serum exosomes |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03627611
GET https://conductscience.org/api/trials/v1/NCT03627611/registered