Trial · NCT03645824
Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF)
NCT03645824, Phase 2, Active not recruiting, Stichting Hemato-Oncologie voor Volwassenen Nederland
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF). Trials, record NCT03645824. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03645824
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Myelofibrosis Treated With Pacritinib Before aSCT. (HOVON134MF)
- NCT number
- NCT03645824
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 61 participants, actual
- Lead sponsor
- Stichting Hemato-Oncologie voor Volwassenen Nederland
- Conditions
- Myelofibrosis
- Interventions
- Pacritinib
- First posted
- 2018-08-24
- Last updated
- 2022-08-22
- Other registries' IDs
- eudract:2015-000195-98
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of patients receiving allo-SCT, with failure within or at day 180 post-transplant. | 2 years | Failure can be defined by one of the following parameters: * Primary graft failure * Acute graft versus host disease grade 3-4 * Secondary graft failure * Death, from any cause |
| Secondary | Adverse events | 5 years | Adverse events will be monitored. |
| Secondary | Progression free survival | 5 years | Progression free survival as time between registration or SCT until progression/relapse or death from any cause |
| Secondary | Overall survival | 5 years | Over all survival, calculated from either registration or SCT. |
| Secondary | Relapse mortality | 5 years | Death due to the disease or after progression |
| Secondary | Non-relapse mortality | 5 years | Death not due to disease or relapse |
| Secondary | Quality of life during and after treatment | 5 years | Quality of life during and after treatment will be recorded by use of the MPN-SAF questionnaire. From a total of 27 questions, the scores (from 0 to 10) from the following 10 questions are added and subsequently averaged to come to a total quality of life score. * fatigue * satisfction after a meal * stomach complaints * not able to perform activities * concentration problems * night sweat * itch * bone pain * fever * sudden weight loss |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03645824
GET https://conductscience.org/api/trials/v1/NCT03645824/registered