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Trial · NCT03660397

Registered outcomes17

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange of 24-h average systolic blood pressure measured at baseline and the end of the trial24 weeksDifference in the change of 24-h average systolic blood pressure between the intervention and control group is to be analysed.
SecondaryChange of 24-h average systolic blood pressure compared with the baseline24 weeksChange of 24-h average systolic blood pressure compared with the baseline at the end of the study (24 weeks) in the intervention group.
SecondaryChange of anti-hypertensive regimen measured at baseline and the end of the trial24 weeksDifference in the change of anti-hypertensive regimen between the intervention and control group is to be analysed.
Secondary
Change of 24-h average diastolic blood pressure, daytime mean systolic blood pressure, daytime mean diastolic blood pressure, and nighttime average systolic and diastolic blood pressure measured at baseline and the end of the trial
24 weeks
Difference in the change of 24-h average diastolic blood pressure, daytime mean systolic blood pressure, daytime mean diastolic blood pressure, and nighttime average systolic and diastolic blood pressure between the intervention and control group is to be analysed.
SecondaryChange of home systolic and diastolic pressure measured at baseline and the end of the trial24 weeksDifference in the change of home systolic and diastolic pressure between the intervention and control group is to be analysed.
SecondaryChange of office systolic and diastolic pressure measured at baseline and the end of the trial24 weeksDifference in the change of office systolic and diastolic pressure between the intervention and control group is to be analysed.
SecondaryChange of blood electrolytes measured at baseline and the end of the trial24 weeksDifference in the change of blood electrolytes between the intervention and control group is to be analysed.
SecondaryChange of plasma and urine adrenal hormones measured at baseline and the end of the trial24 weeksDifference in the change of plasma and urine adrenal hormones between the intervention and control group is to be analysed.
SecondaryChange of plasma renin measured at baseline and the end of the trial24 weeksDifference in the change of plasma renin between the intervention and control group is to be analysed.
SecondaryChange of liver enzymes measured at baseline and the end of the trial24 weeksDifference in the change of liver enzymes (ALT, AST in IU/L) between the intervention and control group is to be analysed.
SecondaryChange of kidney function measured at baseline and the end of the trial24 weeksDifference in the change of serum creatinine in umol/L between the intervention and control group is to be analysed.
SecondaryChange of fasting blood glucose measured at baseline and the end of the trial24 weeksDifference in the change of fasting blood glucose in mmol/L between the intervention and control group is to be analysed.
SecondaryChange of lipids profiles measured at baseline and the end of the trial24 weeksDifference in the change of lipids profiles (TC, HDL-C, LDL-C, TG) in mmol/L between the intervention and control group is to be analysed.
OtherChange of sex hormones measured at baseline and the end of the trial24 weeksDifference in the change of 17-OH, DHEAS, testosterone and estrogen levels between the intervention and control group is to be analysed.
OtherChange of 24-h urine microalbumin measured at baseline and the end of the trial24 weeksDifference in the change of 24-h urine microalbumin, microalbumin/creatinine ratio between the intervention and control group is to be analysed.
OtherChange of echocardiography measured at baseline and the end of the trial24 weeks
Difference in the change of cardiac parameters assessed by echocardiography (IVSd、IVSs、LVPWd, LVPWs, LVEDD, in millimetre(mm), and LVEF(%), LVM in gram) between the intervention and control group is to be analysed.
OtherChange of carotid intima-media thickness assessed by carotid ultrasound at baseline and the end of the trial24 weeksDifference in the change of carotid intima-media thickness(CIMT) assessed by carotid ultrasound between the intervention and control group is to be analysed.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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