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Trial · NCT03660475

Results by group34

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Total Ocular Surface Disease IndexNaltrexone21.17Standard Deviation 17.72score on a scale
Total Ocular Surface Disease IndexPlacebo21.36Standard Deviation 17.16score on a scale
Lissamine Green StainingNaltrexone2.65Standard Deviation 1.10score on a scale
Lissamine Green StainingPlacebo2.59Standard Deviation 1.25score on a scale
Tear Film Break-up TimeNaltrexone2.76Standard Deviation 0.98seconds
Tear Film Break-up TimePlacebo3.48Standard Deviation 2.49seconds
Conjunctival RednessNaltrexone1.0Standard Deviation 0.41score on a scale
Conjunctival RednessPlacebo1.0Standard Deviation 0.45score on a scale
Schirmer's TestNaltrexone8.97Standard Deviation 8.00mm
Schirmer's TestPlacebo12.48Standard Deviation 9.20mm
Cochet-Bonnet Corneal Sensitivity TestNaltrexone59.78Standard Deviation 0.95cm
Cochet-Bonnet Corneal Sensitivity TestPlacebo59.37Standard Deviation 1.44cm
Tear OsmolarityNaltrexone304.31Standard Deviation 14.11mOsm/L
Tear OsmolarityPlacebo310.66Standard Deviation 12.16mOsm/L
Matrix Metalloprotienase-9 (MMP-9) is a Marker of Inflammation.Naltrexone3Participants
Matrix Metalloprotienase-9 (MMP-9) is a Marker of Inflammation.Placebo3Participants
Ocular Discomfort (Scale 1)Naltrexone1.03Standard Deviation 1.10score on a scale
Ocular Discomfort (Scale 1)Placebo1.07Standard Deviation 1.13score on a scale
Ocular Discomfort (Scale 2)Naltrexone1.40Standard Deviation 1.25score on a scale
Ocular Discomfort (Scale 2)Placebo1.45Standard Deviation 1.57score on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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