Trial · NCT03660488
Cefixime for Alternative Syphilis Treatment
NCT03660488, Phase 2, Completed, University of California, Los Angeles; results first posted 2022-07-26
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cefixime for Alternative Syphilis Treatment. Trials, record NCT03660488. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03660488
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cefixime for Alternative Syphilis Treatment
- NCT number
- NCT03660488
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 58 participants, actual
- Lead sponsor
- University of California, Los Angeles
- Conditions
- Syphilis, Early Syphilis
- Interventions
- Cefixime 400 milligram Oral Capsule [Suprax], Benzathine Penicillin G
- First posted
- 2018-09-06
- Last updated
- 2022-07-26
- Results first posted
- 2022-07-26
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Treatment Response | 3 or 6 months after treatment completion | subjects who have a 4-fold decrease (from study entry Rapid plasma reagin) in Rapid plasma reagintiters from baseline at 3 or 6 months will be considered a positive treatment response. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Treatment Response | 3 or 6 months after treatment completion | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Treatment Response | Benzathine Penicillin G | 14 | Participants | ||
| Treatment Response | Cefixime Group | 13 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Benzathine Penicillin G | 31 | |
| Overall Study | STARTED | Cefixime Group | 27 | |
| Overall Study | COMPLETED | Benzathine Penicillin G | 31 | |
| Overall Study | COMPLETED | Cefixime Group | 27 | |
| Overall Study | NOT COMPLETED | Benzathine Penicillin G | 0 | |
| Overall Study | NOT COMPLETED | Cefixime Group | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Mild Skin Rash | Skin and subcutaneous tissue disorders | Benzathine Penicillin G | 31 | ||
| serious | Mild Skin Rash | Skin and subcutaneous tissue disorders | Cefixime Group | 1 | 27 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Benzathine Penicillin G | 0 | 31 |
| Total, all-cause mortality | Cefixime Group | 0 | 27 |
| Total, other adverse events | Benzathine Penicillin G | 0 | 31 |
| Total, other adverse events | Cefixime Group | 0 | 27 |
| Total, serious adverse events | Benzathine Penicillin G | 0 | 31 |
| Total, serious adverse events | Cefixime Group | 1 | 27 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 33298143 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Benzathine Penicillin G vs Cefixime Group: Treatment Response | Trial comparisons |
| Benzathine Penicillin G vs Cefixime Group: deaths from any cause | Trial comparisons |
| Benzathine Penicillin G vs Cefixime Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03660488
GET https://conductscience.org/api/trials/v1/NCT03660488/registered