Trial · NCT03663855
Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria
NCT03663855, Phase 2, Completed, NYU Langone Health; results first posted 2021-12-17
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria. Trials, record NCT03663855. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03663855
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Increasing Doses of Tiopronin on Cystine Capacity in Patients With Cystinuria
- NCT number
- NCT03663855
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 10 participants, actual
- Lead sponsor
- NYU Langone Health
- Conditions
- Cystinuria
- Interventions
- Tiopronin
- First posted
- 2018-09-10
- Last updated
- 2021-12-17
- Results first posted
- 2021-12-17
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Cystine Capacity From Baseline | Baseline; Day 7 | This measure reflects the ability of urine to take up more cystine |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Cystine Capacity From Baseline | Baseline; Day 7 | mg/L | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Cystine Capacity From Baseline | Cystinuria Patients | Phase 1 | -63.6 | Standard Deviation 24.8 | mg/L |
| Change in Cystine Capacity From Baseline | Cystinuria Patients | Phase 2 | 76 | Standard Deviation 18.1 | mg/L |
| Change in Cystine Capacity From Baseline | Cystinuria Patients | Phase 3 | 53.4 | Standard Deviation 17.7 | mg/L |
| Change in Cystine Capacity From Baseline | Cystinuria Patients | Phase 4 | 103.1 | Standard Deviation 27.4 | mg/L |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Cystinuria Patients | 10 | |
| Overall Study | COMPLETED | Cystinuria Patients | 10 | |
| Overall Study | NOT COMPLETED | Cystinuria Patients | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Cystinuria Patients | 0 | 10 |
| Total, other adverse events | Cystinuria Patients | 0 | 10 |
| Total, serious adverse events | Cystinuria Patients | 0 | 10 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03663855
GET https://conductscience.org/api/trials/v1/NCT03663855/registered