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Trial · NCT03677141

Results by group230

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Complete Response (CR) Rate at the Time of Primary Response Assessment (PRA) Based on Positron Emission Tomography - Computed Tomography (PET-CT) as Determined by Independent Review Committee (IRC)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)72.595% Confidence Interval 56.11 to 85.40Percentage of participants
Complete Response (CR) Rate at the Time of Primary Response Assessment (PRA) Based on Positron Emission Tomography - Computed Tomography (PET-CT) as Determined by Independent Review Committee (IRC)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)77.395% Confidence Interval 54.63 to 92.18Percentage of participants
CR Rate at PRA Based on CT Only as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOP50.095% Confidence Interval 33.80 to 66.20Percentage of participants
CR Rate at PRA Based on CT Only as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)47.595% Confidence Interval 31.51 to 63.87Percentage of participants
CR Rate at PRA Based on CT Only as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)31.895% Confidence Interval 13.86 to 54.87Percentage of participants
Overall Response Rate (ORR) at PRA Based on PET-CT as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOP87.595% Confidence Interval 73.20 to 95.81Percentage of participants
Overall Response Rate (ORR) at PRA Based on PET-CT as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)80.095% Confidence Interval 64.35 to 90.95Percentage of participants
Overall Response Rate (ORR) at PRA Based on PET-CT as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)77.395% Confidence Interval 54.63 to 92.18Percentage of participants
ORR at PRA Based on CT Only as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOP85.095% Confidence Interval 70.16 to 94.29Percentage of participants
ORR at PRA Based on CT Only as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)72.595% Confidence Interval 56.11 to 85.40Percentage of participants
ORR at PRA Based on CT Only as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)81.895% Confidence Interval 59.72 to 94.81Percentage of participants
Best ORR Based on PET-CT and/or CT Scan as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOP95.095% Confidence Interval 83.08 to 99.39Percentage of responders
Best ORR Based on PET-CT and/or CT Scan as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)85.095% Confidence Interval 70.16 to 94.29Percentage of responders
Best ORR Based on PET-CT and/or CT Scan as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)95.595% Confidence Interval 77.16 to 99.88Percentage of responders
Duration of Response (DOR) as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOPNAFull Range 0 to 28Months
Duration of Response (DOR) as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)NAFull Range 0 to 28Months
Duration of Response (DOR) as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)NAFull Range 1 to 27Months
Progression-free Survival (PFS) as Determined by the Investigator (Phase II)Group C: Phase II Mosunetuzumab + CHOPNAFull Range 0 to 31Months
Progression-free Survival (PFS) as Determined by the Investigator (Phase II)Arm 1: Phase II Mosunetuzumab + CHP-Pola (Randomized)NAFull Range 0 to 30Months
Progression-free Survival (PFS) as Determined by the Investigator (Phase II)Arm 2: Phase II Rituximab + CHP-Pola (Randomized)NAFull Range 3 to 30Months

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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