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Trial · NCT03703271

Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia

NCT03703271, Phase 2, Recruiting, Women's Hospital School Of Medicine Zhejiang University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia. Trials, record NCT03703271. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03703271

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Study of Hysteroscopic Repeat Curettage as the First-line Treatment in Low-risk Postmolar Gestational Trophoblastic Neoplasia
NCT number
NCT03703271
Status
Recruiting
Phases
Phase 2
Enrollment
70 participants, estimated
Lead sponsor
Women's Hospital School Of Medicine Zhejiang University
Conditions
Gestational Trophoblastic Neoplasia
Interventions
Methotrexate, hysteroscopic repeat curettage
First posted
2018-10-11
Last updated
2026-10-21

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryThe ultimate complete response rate2 years
The investigators may calculate the ultimate complete response rate, defined as the proportion of patients who achieve sustained normalisation of serum hCG without requiring escalation to multi-agent chemotherapy at the predefined trial endpoint.
Secondarychemotherapy-sparing rate2 yearsThe investigators may calculate the rate of response after the initial treatment of hysteroscopic repeat curettage without chemotherapy
SecondaryComplications of hysteroscopic repeat curettage surgery2 yearsThe investigators may record the complications of hysteroscopic repeat curettage surgery
SecondarySeverity of adverse events as assessed by the WHO2 yearsThe investigators may record the adverse events of chemotherapy as assessed by the WHO
SecondaryOverall Survival Rate (OR)2 yearsOverall Survival Rate of the two group patients
SecondaryOvarian functional evaluation2 yearsThe investigators may test serum level of anti-mullerian hormone (AMH) every 6 months.
SecondaryThe pregnancy rate2 yearsTo calculate the pregnancy rate in an actuarial manner using the Kaplan-Meier method at the end of the trail
SecondaryMenstrual cycle resuming rate2 yearsThe investigators record the time of menstrual cycle resuming after chemotherapy

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03703271

GET https://conductscience.org/api/trials/v1/NCT03703271/registered