Trial · NCT03710941
Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis
NCT03710941, Phase 2, Withdrawn, Regeneron Pharmaceuticals
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis. Trials, record NCT03710941. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03710941
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis
- NCT number
- NCT03710941
- Status
- Withdrawn
- Phases
- Phase 2
- Enrollment
- 0 participants, actual
- Lead sponsor
- Regeneron Pharmaceuticals
- Conditions
- Sporadic Inclusion Body Myositis
- Interventions
- REGN2477+REGN1033, Matching placebo
- First posted
- 2018-10-18
- Last updated
- 2019-04-29
- Other registries' IDs
- eudract:2018-002853-31
Source ClinicalTrials.gov
Registered outcomes23
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percent change in total lean mass as measured by dual-energy X-ray absorptiometry (DXA) | Up to Week 20 | |
| Secondary | Change in the Inclusion Body Myositis-Functional Rating Scale (IBM-FRS) | Up to Week 26 | |
| Secondary | Change in the Sporadic inclusion body myositis (sIBM) Physical Functioning Assessment (sIFA) | Up to Week 26 | |
| Secondary | Incidence and severity of treatment-emergent adverse events (TEAEs) | Up to Week 30 | |
| Secondary | Percent change in total and regional body composition (including lean mass and fat mass) as measured by DXA | Up to Week 30 | |
| Secondary | Absolute change in total and regional body composition (including lean mass and fat mass) as measured by DXA | Up to Week 30 | |
| Secondary | Change in the 1-repetition maximum (1-RM) chest press strength | Up to Week 26 | |
| Secondary | Change in hand-grip strength as measured by dynamometry | Up to Week 26 | |
| Secondary | Change in distance walked in the 6-minute walk test (6MWT) | Up to Week 26 | |
| Secondary | Change in time to complete the 10-meter walk test (10MWT) | Up to Week 26 |
1 to 10 of 23Source ClinicalTrials.gov
See all 23 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03710941
GET https://conductscience.org/api/trials/v1/NCT03710941/registered?page=2