Trial · NCT03718273
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 16 of 16
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Heart rate reduction. | 3 months | Reduction of the mean daytime heart rate registered in Holter- electrocardiogram (ECG) after treatment with Ivabradine or Digoxin. |
| Primary | Serious adverse events | 3 months | Proportion of patients experiencing syncope, severe bradycardia or any serious adverse reaction requiring hospitalization, emergency visit or death of the patient during treatment with Ivabradine or Digoxin. |
| Secondary | Reduction in the scale of atrial fibrillation (AF) symptoms according to the European Hearth Rhythm Association (EHRA) Score modified. | Months 1 and 3. | Percentage of patients who experience a reduction in the scale of atrial fibrillation. symptoms according to the EHRA Score modified. |
| Secondary | 6 minute walk test (6MWT). | Baseline and after 3 months. | Increase in meters in the 6MWT. |
| Secondary | Quality-of-Life Short Form 36 (SF-36) Health Survey (QoL SF-36) Score. | At baseline and 3 months. | Increase in the score obtained in global quality of life parameters analyzed by the SF-36 questionnaire. |
| Secondary | The Atrial Fibrillation Effect on Quality-of-Life (QoL AFEQT) score. | At baseline and 3 months | Increase in the score obtained in parameters of quality of life quality of life associated with AF analyzed by the AFEQT questionnaire. |
| Secondary | Reduction of the daytime Health rate. | 1 month | Reduction of the average daytime Heart Rate (HR) recorded in Holter-ECG |
| Secondary | Reduction of resting Health Rate. | 1 and 3 months | Reduction of resting heart rate (HR) recorded on one electrocardiogram (ECG). |
| Secondary | Reduction of the maximum heart rate (HR) recorded. | 1 and 3 months | Reduction of the maximum HR recorded in Holter-ECG |
| Secondary | Reduction of the mean HR recorded. | 1 and 3 months | Reduction of the mean HR in 24 hours recorded in Holter-ECG . |
| Secondary | Reduction of the HR delta. | 1 and 3 months | Reduction of the HR delta (difference between maximum HR and mean HR in 24 hours) recorded in Holter-ECG. |
| Secondary | Reduction of HR in moderate exercise. | 3 months | Reduction of HR in moderate exercise (maximum HR measured by Holter-ECG during the 6-minute walk test. |
| Secondary | Percentage of patients with non-severe bradycardia. | 1 and 3 months | Percentage of patients who experience non-severe bradycardia during the study treatment. |
| Secondary | Percentage of patients who experience any adverse reaction. | 1 and 3 months | Percentage of patients who experience any adverse reaction to the study drugs. |
| Secondary | Percentage of patients who voluntarily abandon the study drugs. | 3 months | Percentage of patients who voluntarily abandon the study drugs. |
| Secondary | Proportion of hospitalizations, emergency visits and mortality due to a major cardiovascular event. | 3 months | Proportion of patients experiencing hospitalizations, emergency visits and mortality due to a major cardiovascular event during treatment with the study drug. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT03718273/registered