Trial · NCT03720990
Smith-Lemli-Opitz Syndrome and Cholic Acid
NCT03720990, Phase 1, Phase 2, Completed, University of Nebraska; results first posted 2023-12-13
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Smith-Lemli-Opitz Syndrome and Cholic Acid. Trials, record NCT03720990. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03720990
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Smith-Lemli-Opitz Syndrome and Cholic Acid
- NCT number
- NCT03720990
- Status
- Completed
- Phases
- Phase 1, Phase 2
- Enrollment
- 12 participants, actual
- Lead sponsor
- University of Nebraska
- Conditions
- Smith-Lemli-Opitz Syndrome
- Interventions
- Cholic Acid
- First posted
- 2018-10-26
- Last updated
- 2024-04-30
- Results first posted
- 2023-12-13
- Limitations and caveats
- No limitations or caveats.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Plasma Cholesterol | 8 weeks | Plasma cholesterol will be measured. Response to cholic acid treatment will consist of a change in plasma cholesterol. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Plasma Cholesterol | 8 weeks | change (%) compared to baseline | MEAN |
Source ClinicalTrials.gov
Results by group1
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Plasma Cholesterol | Cholic Acid | 37.8 | Standard Deviation 22.4 | change (%) compared to baseline |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Cholic Acid | 12 | |
| Overall Study | COMPLETED | Cholic Acid | 12 | |
| Overall Study | NOT COMPLETED | Cholic Acid | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Cholic Acid | 0 | 12 |
| Total, other adverse events | Cholic Acid | 0 | 12 |
| Total, serious adverse events | Cholic Acid | 0 | 12 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03720990
GET https://conductscience.org/api/trials/v1/NCT03720990/registered