Physical Training Induced Plasticity of Motor Control Mechanisms in Parkinson's Disease Patients
NCT03753503, Not applicable, Completed, Wroclaw University of Health and Sport Sciences
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Physical Training Induced Plasticity of Motor Control Mechanisms in Parkinson's Disease Patients | ClinicalTrials.gov |
| NCT number | NCT03753503 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 60 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Wroclaw University of Health and Sport Sciences | ClinicalTrials.gov |
| Conditions | Parkinson Disease, Physical Activity | ClinicalTrials.gov |
| Interventions | exercise, conventional physical therapy | ClinicalTrials.gov |
| First posted | 2018-11-27 | ClinicalTrials.gov |
| Last updated | 2018-12-03 | ClinicalTrials.gov |
Registered outcomes 43
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Electroencephalography (EEG) - electrical activity of brain cortex recorded from scalp using surface electrodes. | Baseline | To evaluate neurophysiological functions of brain cortical structures, electroencephalography (EEG - electrical activity of brain cortex) will be recorded from scalp using 64-chanel system. The recordings will be conducted during bimanual motor tasks and at rest. The recordings will be expressed in microvolts \[µV\]. | ClinicalTrials.gov |
| Primary | Electroencephalography (EEG) - electrical activity of brain cortex recorded from scalp using surface electrodes. | 1-week-post HIIT cycle | To evaluate neurophysiological functions of brain cortical structures, electroencephalography (EEG - electrical activity of brain cortex) will be recorded from scalp using 64-chanel system. The recordings will be conducted during bimanual motor tasks and at rest. The recordings will be expressed in microvolts \[µV\]. | ClinicalTrials.gov |
| Primary | Electroencephalography (EEG) - electrical activity of brain cortex recorded from scalp using surface electrodes. | 1-month-post HIIT cycle | To evaluate neurophysiological functions of brain cortical structures, electroencephalography (EEG - electrical activity of brain cortex) will be recorded from scalp using 64-chanel system. The recordings will be conducted during bimanual motor tasks and at rest. The recordings will be expressed in microvolts \[µV\]. | ClinicalTrials.gov |
| Primary | Electromyography (EMG) - recordings of electrical activity of skeletal muscles using surface electrodes. | Baseline | To evaluate neurophysiological functions of muscles engaged in an activity (hand and forearm muscles), electromyography (EMG - recordings of electrical activity of skeletal muscles) will be collected using surface electrodes, during bimanual motor tasks and at rest. The recordings will be expressed in milivolts \[mV\]. | ClinicalTrials.gov |
| Primary | Electromyography (EMG) - recordings of electrical activity of skeletal muscles using surface electrodes. | 1-week-post HIIT cycle | To evaluate neurophysiological functions of muscles engaged in an activity (hand and forearm muscles), electromyography (EMG - recordings of electrical activity of skeletal muscles) will be collected using surface electrodes, during bimanual motor tasks and at rest. The recordings will be expressed in milivolts \[mV\]. | ClinicalTrials.gov |
| Primary | Electromyography (EMG) - recordings of electrical activity of skeletal muscles using surface electrodes. | 1-month-post HIIT cycle | To evaluate neurophysiological functions of muscles engaged in an activity (hand and forearm muscles), electromyography (EMG - recordings of electrical activity of skeletal muscles) will be collected using surface electrodes, during bimanual motor tasks and at rest. The recordings will be expressed in milivolts \[mV\]. | ClinicalTrials.gov |
| Primary | BDNF - brain derived neurotrophic factor | Baseline | BDNF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | BDNF - brain derived neurotrophic factor | 1-week-post HIIT cycle | BDNF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | BDNF - brain derived neurotrophic factor | 1-month-post HIIT cycle | BDNF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | NGF - nerve growth factor | Baseline | NGF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | NGF - nerve growth factor | 1-week-post HIIT cycle | NGF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | NGF - nerve growth factor | 1-month-post HIIT cycle | NGF secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | IGF 1 - insulin-like growth factor 1 | Baseline | IGF 1 secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | IGF 1 - insulin-like growth factor 1 | 1-week-post HIIT cycle | IGF 1 secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | IGF 1 - insulin-like growth factor 1 | 1-month-post HIIT cycle | IGF 1 secretion level in blood expressed in \[pg/mL\] | ClinicalTrials.gov |
| Primary | Force measurements of both hands' index fingers motor control | Baseline | force development measurements of self initiated bimanual anti-phase index finger movements, using force transducers system. The force will be expressed in \[N\], the time of force development in \[s\] and the rate of force development in \[N/s\]. | ClinicalTrials.gov |
| Primary | Force measurements of both hands' index fingers motor control | 1-week-post HIIT cycle | force development measurements of self initiated bimanual anti-phase index finger movements, using force transducers system. The force will be expressed in \[N\], the time of force development in \[s\] and the rate of force development in \[N/s\]. | ClinicalTrials.gov |
| Primary | Force measurements of both hands' index fingers motor control | 1-month-post HIIT cycle | force development measurements of self initiated bimanual anti-phase index finger movements, using force transducers system. The force will be expressed in \[N\], the time of force development in \[s\] and the rate of force development in \[N/s\]. | ClinicalTrials.gov |
| Primary | Force measurements of bimanual dexterity function | Baseline | force development measurements of self initiated bimanual anti-phase hand grip-load function, using force transducers system. The force will be expressed in \[N\], the time of force development in \[s\] and the rate of force development in \[N/s\]. | ClinicalTrials.gov |
| Primary | Force measurements of bimanual dexterity function | 1-week-post HIIT cycle | force development measurements of self initiated bimanual anti-phase hand grip-load function, using force transducers system.The force will be expressed in \[N\], the time of force development in \[s\] and the rate of force development in \[N/s\]. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 2
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)