Trial · NCT03754309
A Study of KY1005 in Patients With Moderate to Severe Atopic Dermatitis
NCT03754309, Phase 2, Completed, Kymab Limited
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. A Study of KY1005 in Patients With Moderate to Severe Atopic Dermatitis. Trials, record NCT03754309. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03754309
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of KY1005 in Patients With Moderate to Severe Atopic Dermatitis
- NCT number
- NCT03754309
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 89 participants, actual
- Lead sponsor
- Kymab Limited
- Conditions
- Dermatitis, Atopic
- Interventions
- KY1005, Placebo
- First posted
- 2018-11-27
- Last updated
- 2023-01-27
- Other registries' IDs
- eudract:2018-002299-41
Source ClinicalTrials.gov
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage change in Eczema Area and Severity Index (EASI) | Baseline to day 113 | |
| Primary | Incidence of treatment-emergent adverse events (TEAEs) | Baseline to day 113 | |
| Secondary | Percentage and absolute change from Baseline in EASI over time | Baseline to day 113 | |
| Secondary | Change in epidermal thickness | Baseline to day 113 | |
| Secondary | Change in keratin 16 staining of skin biopsies | Baseline to day 113 | |
| Secondary | Percentage of patients with at least a 50% reduction in EASI (EASI 50) | Baseline to day 113 | |
| Secondary | Percentage of patients with at least a 75% reduction in EASI (EASI 75) | Baseline to day 113 | |
| Secondary | Percentage of patients with at least a 90% reduction in EASI (EASI 90) | Baseline to day 113 | |
| Secondary | Change in Validated Investigator Global Assessment (vIGA) | Baseline to day 113 | |
| Secondary | Percentage of patients with a response of vIGA 0 or 1 | Baseline to day 113 |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03754309
GET https://conductscience.org/api/trials/v1/NCT03754309/registered