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Trial · NCT03776175

Results by group56

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Whole Liver Proton Density Fat Fraction (PDFF) at Day 42Placebo8.1490% Confidence Interval -8.56 to 27.89percent change
Percent Change From Baseline in Whole Liver Proton Density Fat Fraction (PDFF) at Day 42PF-05221304 15mg + Placebo-40.0190% Confidence Interval -47.00 to -32.09percent change
Percent Change From Baseline in Whole Liver Proton Density Fat Fraction (PDFF) at Day 42PF-06865571 300 mg + Placebo-30.1490% Confidence Interval -37.97 to -21.33percent change
Percent Change From Baseline in Whole Liver Proton Density Fat Fraction (PDFF) at Day 42PF-05221304 15 mg + PF-06865571 300 mg-40.1390% Confidence Interval -46.58 to -32.90percent change
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PlaceboParticipants With AEs3Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-05221304 15mg + PlaceboParticipants With AEs10Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-06865571 300 mg + PlaceboParticipants With AEs10Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-05221304 15 mg + PF-06865571 300 mgParticipants With AEs10Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PlaceboParticipants With SAEs0Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-05221304 15mg + PlaceboParticipants With SAEs0Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-06865571 300 mg + PlaceboParticipants With SAEs0Participants
Number of Participants With Treatment Emergent Adverse Events (AEs) and Serious Adverse Events (SAEs)PF-05221304 15 mg + PF-06865571 300 mgParticipants With SAEs1Participants
Number of Participants With Laboratory AbnormalitiesPlacebo6Participants
Number of Participants With Laboratory AbnormalitiesPF-05221304 15mg + Placebo17Participants
Number of Participants With Laboratory AbnormalitiesPF-06865571 300 mg + Placebo11Participants
Number of Participants With Laboratory AbnormalitiesPF-05221304 15 mg + PF-06865571 300 mg6Participants
Maximum Change (Increase or Decrease) From Baseline to Post-last Dose of Study Drug in Vital Signs: Blood PressurePlaceboMaximum increase: Systolic blood pressure10.8Standard Deviation 6.59millimeter of mercury
Maximum Change (Increase or Decrease) From Baseline to Post-last Dose of Study Drug in Vital Signs: Blood PressurePF-05221304 15mg + PlaceboMaximum increase: Systolic blood pressure7.0Standard Deviation 7.77millimeter of mercury
Maximum Change (Increase or Decrease) From Baseline to Post-last Dose of Study Drug in Vital Signs: Blood PressurePF-06865571 300 mg + PlaceboMaximum increase: Systolic blood pressure9.6Standard Deviation 11.38millimeter of mercury
Maximum Change (Increase or Decrease) From Baseline to Post-last Dose of Study Drug in Vital Signs: Blood PressurePF-05221304 15 mg + PF-06865571 300 mgMaximum increase: Systolic blood pressure7.5Standard Deviation 12.58millimeter of mercury

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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