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Trial · NCT03779594

Acetazolamide for Treating NPH in Shunt-candidates Patients

NCT03779594, Phase 2, Unknown, Rabin Medical Center

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Acetazolamide for Treating NPH in Shunt-candidates Patients. Trials, record NCT03779594. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03779594

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Acetazolamide for Treating NPH in Shunt-candidates Patients
NCT number
NCT03779594
Status
Unknown
Phases
Phase 2
Enrollment
15 participants, estimated
Lead sponsor
Rabin Medical Center
Conditions
Normal Pressure Hydrocephalus
Interventions
Acetazolamide
First posted
2018-12-19
Last updated
2018-12-19

Source ClinicalTrials.gov

Registered outcomes6

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange from Baseline GaitBaseline, week 4
Change from Baseline gait will be evaluated by the neurosurgery department's physiotherapist, using the timed-up-and-go (TUG) test (measured in seconds, higher values represent a worse outcome). Patients will be evaluated at baseline (before treatment is started) and again before surgery (4 weeks later).
PrimaryChange from Baseline BalanceBaseline, week 4
Change from Baseline balance will be evaluated by the neurosurgery department's physiotherapist, using the TINETTI balance assessment score. (0-28 scale, higher values represent a better outcome). Patients will be evaluated at baseline (before treatment is started) and again before surgery (4 weeks later).
SecondaryChange from Baseline concentration functionBaseline, week 4
concentration function will be evaluated by the neurosurgery department's neuropsychologist using the color trial test (seconds, higher values represent a worse outcome). Patients will be evaluated at baseline (before treatment is started) and again before surgery (4 weeks later).
SecondaryChange from Baseline visuospatial functionBaseline, week 4
visuospatial function will be evaluated by the neurosurgery department's neuropsychologist using the clock drawing test (0-10 scale, higher values represent a better outcome). Patients will be evaluated at baseline (before treatment is started) and again before surgery (4 weeks later).
SecondaryChange from Baseline verbal fluencyBaseline, week 4
verbal fluency will be evaluated by the neurosurgery department's neuropsychologist using the verbal fluency test (Controlled Oral Word Association Test, number of words in one minute, higher values represent a better outcome). Patients will be evaluated at baseline (before treatment is started) and again before surgery (4 weeks later).
Otheradverse effectsweek 2-6All adverse effects that may be attributed to the treatment will be recorded

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers11

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
12137677BACKGROUNDPubMed
21235310BACKGROUNDPubMed
21849644BACKGROUNDPubMed
23975646BACKGROUNDPubMed
24634454BACKGROUNDPubMed
24682964BACKGROUNDPubMed
25928394BACKGROUNDPubMed
25934242BACKGROUNDPubMed
26587993BACKGROUNDPubMed
26644048BACKGROUNDPubMed

1 to 10 of 11

See all 11 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests2

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Clock Drawing TaskSecondary outcomeConductCognition
Verbal FluencySecondary outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03779594

GET https://conductscience.org/api/trials/v1/NCT03779594/registered