Trial · NCT03779646
Bisoprolol in DMD Early Cardiomyopathy
NCT03779646, Phase 2, Phase 3, Unknown, Peking Union Medical College Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Bisoprolol in DMD Early Cardiomyopathy. Trials, record NCT03779646. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03779646
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Bisoprolol in DMD Early Cardiomyopathy
- NCT number
- NCT03779646
- Status
- Unknown
- Phases
- Phase 2, Phase 3
- Enrollment
- 42 participants, estimated
- Lead sponsor
- Peking Union Medical College Hospital
- Conditions
- Duchenne Muscular Dystrophy, Cardiomyopathy, Dilated
- Interventions
- Bisoprolol Fumarate
- First posted
- 2018-12-19
- Last updated
- 2022-09-28
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Calculate the change of left ventricle global longitudinal strain in cardiac MR | baseline and 12 months | Calculate the change of left ventricle global longitudinal strain in cardiac MR from baseline to 12months for each patients |
| Secondary | Calculate the change of left ventricular ejection fraction in cardia MR | baseline and 12 months | Calculate the change of left ventricular ejection fraction in cardia MR from baseline to 12months for each patients |
| Secondary | Calculate the change of ventricle late gadolinium enhancement area in cardia MR | baseline and 12 months | Calculate the change of ventricle late gadolinium enhancement area in cardia MR from baseline to 12months for each patients |
| Secondary | Calculate the change of the level of high-sensitivity cardiac troponin I | baseline and 6months, 12 months | Calculate the change of the level of high-sensitivity cardiac troponin I from baseline to 6months and 12months for each patients |
| Secondary | Calculate the change of the level of NT-proBNP | baseline and 6months, 12 months | Calculate the change of the level of NT-proBNP from baseline to 6months and 12months for each patients |
| Secondary | Calculate the change of E/A ratio assessed by echocardiography | baseline and 12 months | Calculate the change of diastolic dysfunction (E/A ratio) assessed by echocardiography from baseline to 12months for each patients |
| Secondary | Change of the resting heart rate | baseline and 6months, 12 months | Calculate the change of the resting heart rate from baseline to 6months and 12months for each patients |
| Other | Number of participants with All cause mortality, cardiac death, or hospitalized due to heart problem | 12 months | Number of Subjects with All cause mortality, cardiac death, or hospitalized due to heart problem at the end of study |
| Other | Number of participants with bisoprolol-related adverse events as assessed by the following definition | 12 months | Bisoprolol treatment-related adverse events including the dizziness, bradyarrhythmia (resting heart rate lower than 55bpm)，II and III degree atrioventricular block，hypotension |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03779646
GET https://conductscience.org/api/trials/v1/NCT03779646/registered