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Trial · NCT03803124

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRenal plasma flow (RPF)Two hours after trial medicine intakeEstimated by posterior Technetium-99m diethylenetriamine penta-acetic acid (99-mTc-DTPA) renography 2 hours after trial medicine intake. (unit of measurement= ml/min)
SecondaryCentral and brachial blood pressures (BP)Measured every 15 minutes during the examination dayMeasured using Mobil-O-Graph® PWA (unit of measurement= mmHg)
SecondaryGlomerular filtration rate (GFR)Two hours after trial medicine intakeEstimated by posterior Technetium-99m diethylenetriamine penta-acetic acid (99-mTc-DTPA) renography 2 hours after trial medicine intake. (unit of measurement= ml/min)
SecondaryFiltration fraction (FF)Two hours after trial medicine intakeEstimated by posterior Technetium-99m diethylenetriamine penta-acetic acid (99-mTc-DTPA) renography 2 hours after trial medicine intake. (unit of measurement= %)
SecondaryPlasma concentration of vasopressin (p-AVP)Measured before and 3 hours after trial medicine intakeBlood samples (unit of measurement= pg/ml)
SecondaryPlasma concentration of aldosterone (p-Aldo)Measured before and 3 hours after trial medicine intakeBlood samples (unit of measurement= pmol/ml)
SecondaryPlasma concentration of angiotensin II (p-AngII)Measured before and 3 hours after trial medicine intakeBlood samples (unit of measurement= pg/ml)
SecondaryPlasma concentration of renin (PRC)Measured before and 3 hours after trial medicine intakeBlood samples (unit of measurement= pg/ml)
SecondaryUrine excretion of aquaporin 2 (u-AQP2)Measured before and 3 hours after trial medicine intakeUrine sample (unit of measurement= ng/ml)
SecondaryUrine output (OU)Measured before and 3 hours after trial medicine intakeUrine sample (unit of measurement= ml/min)
SecondaryUrine osmolality (U-osm)measured before and 3 hours after trial medicine intakeUrine sample (unit of measurement= mosmol/kg)
SecondaryFractional excretion of sodium (FENa)Measured before and 3 hours after trial medicine intakeBlood and urine sample (unit of measurement= %)
SecondaryAlbumin excretion rateMeasured before and 3 hours after trial medicine intakeBlood and urine sample (unit of measurement= mg/min)

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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