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Trial · NCT03819153

Results by group46

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Number of Participants From Time of Randomization to First Occurrence of Onset of Persistent ≥50% Reduction in eGFR(CKD-EPI); Onset of Persistent eGFR(CKD-EPI) <15mL/Min/1.73m^2; Initiation of Chronic Renal Replacement Therapy; Renal Death; CV Death
Semaglutide331Participants
Number of Participants From Time of Randomization to First Occurrence of Onset of Persistent ≥50% Reduction in eGFR(CKD-EPI); Onset of Persistent eGFR(CKD-EPI) <15mL/Min/1.73m^2; Initiation of Chronic Renal Replacement Therapy; Renal Death; CV Death
Placebo410Participants
Annual Rate of Change in eGFR (CKD-EPI) (Total eGFR Slope)Semaglutide-2.19Standard Error 0.1(mL/min/1.73 m^2)/year
Annual Rate of Change in eGFR (CKD-EPI) (Total eGFR Slope)Placebo-3.36Standard Error 0.1(mL/min/1.73 m^2)/year
Number of Participants From Time of Randomization to Occurrence of Onset of Persistent ≥50% Reduction in eGFR (CKD-EPI)Semaglutide165Participants
Number of Participants From Time of Randomization to Occurrence of Onset of Persistent ≥50% Reduction in eGFR (CKD-EPI)Placebo213Participants
Number of Participants From Time of Randomization to Occurrence of Onset of Persistent eGFR (CKD-EPI) <15mL/Min/1.73m^2Semaglutide92Participants
Number of Participants From Time of Randomization to Occurrence of Onset of Persistent eGFR (CKD-EPI) <15mL/Min/1.73m^2Placebo110Participants
Number of Participants From Time of Randomization to Occurrence of Initiation of Chronic Renal Replacement TherapySemaglutide87Participants
Number of Participants From Time of Randomization to Occurrence of Initiation of Chronic Renal Replacement TherapyPlacebo100Participants
Number of Participants From Time of Randomization to Occurrence of Renal DeathSemaglutide5Participants
Number of Participants From Time of Randomization to Occurrence of Renal DeathPlacebo5Participants
Number of Participants From Time of Randomization to Occurrence of CV DeathSemaglutide123Participants
Number of Participants From Time of Randomization to Occurrence of CV DeathPlacebo169Participants
Annual Rate of Change in eGFR (Chronic Kidney Disease CKD-EPI) (Chronic eGFR Slope)Semaglutide-2.36Standard Error 0.1mL/min/1.73 m^2
Annual Rate of Change in eGFR (Chronic Kidney Disease CKD-EPI) (Chronic eGFR Slope)Placebo-3.30Standard Error 0.1mL/min/1.73 m^2
Change From Baseline in eGFR (CKD-EPI) at Week 12Semaglutide-1.07Standard Deviation 8.16mL/min/1.73m^2
Change From Baseline in eGFR (CKD-EPI) at Week 12Placebo-1.07Standard Deviation 7.73mL/min/1.73m^2
Change From Baseline in eGFR (Cystatin C CKD-EPI) at Week 104Semaglutide-2.1Standard Deviation 11.4mL/min/1.73m^2
Change From Baseline in eGFR (Cystatin C CKD-EPI) at Week 104Placebo-5.4Standard Deviation 9.7mL/min/1.73m^2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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