ConductScience.org, home

Trial · NCT03827239

Investigation of the Effects of Sedentary Behaviour and Moderate Exercise on Glucose Tolerance and Insulin Sensitivity

NCT03827239, Not applicable, Terminated, University of Prince Edward Island

3 sourcestrials-2026-11-12-0.5.0

Download JSON
Cite this record

ConductScience Library. Investigation of the Effects of Sedentary Behaviour and Moderate Exercise on Glucose Tolerance and Insulin Sensitivity. Trials, record NCT03827239. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03827239

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Investigation of the Effects of Sedentary Behaviour and Moderate Exercise on Glucose Tolerance and Insulin Sensitivity
NCT number
NCT03827239
Status
Terminated
Phases
Not applicable
Enrollment
6 participants, actual
Lead sponsor
University of Prince Edward Island
Conditions
Sedentary Lifestyle, Insulin Sensitivity, Glucose Metabolism
Interventions
Activity/Moderate Exercise
First posted
2019-02-01
Last updated
2021-01-29

Source ClinicalTrials.gov

Registered outcomes10

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Insulin levelsPre-prandial baseline (12 hours fasted) and 3 hours post-prandial on each of two testing days
The change in blood insulin levels from baseline (12 hours fasted) to 3-hours post-prandial will be determined from blood serum using a human metabolic hormone multiplex panel (Luminex xMAP technology).
PrimaryChange in concentration of C-peptidePre-prandial baseline (12 hours fasted) and 3 hours post-prandial on each of two testing days
The change in blood C-peptide levels from baseline (12 hours fasted) to 3-hours post-prandial will be determined from blood serum using a human metabolic hormone multiplex panel (Luminex xMAP technology).
PrimaryChanges in blood glucose levelsBaseline and every 30-60 minutes over 3 hours (6 timepoints per test day)Blood glucose levels will be determined at pre-prandial baseline and over the following 3-hour testing period using hand-held blood glucose meters.
PrimaryChange in metabolomic response to a test mealPre-prandial and 3-hours post test meal through study completion
Targeted metabolomics analysis of approximately 139 metabolites in blood serum by LC-MS/MS to generate a metabolomic profile in response to a high-fat and high-carbohydrate test meal. Metabolites to be determined are categorized as biogenic amines, amino acids, histidines, carboxylic acids, acylcarnitines, glycerophospholipids and organic acids.
SecondaryImmediate effects of short-term sedentary behaviour on cognitive function3 hours post-activity (sedentary behaviour or exercise) on test days through study completionAssessing cognitive abilities using the Stroop Test.
SecondaryImmediate effects of short-term sedentary behaviour on cognitive function3 hours post-activity (sedentary behaviour or exercise) on test days through study completionAssessing cognitive abilities using the Iowa Trail Making Test.
SecondaryImmediate effects of short-term sedentary behaviour on cognitive function3 hours post-activity (sedentary behaviour or exercise) on test days through study completionAssessing cognitive abilities using the Digit-Span test.
SecondaryImmediate effects of short-term sedentary behaviour on cognitive function3 hours post-activity (sedentary behaviour or exercise) on test days through study completionAssessing cognitive abilities using the N-back test.
SecondaryImmediate effects of short-term sedentary behaviour on cognitive function3 hours post-activity (sedentary behaviour or exercise) on test days through study completionAssessing cognitive abilities using the Flankers test.
SecondaryGene expression levels in isolated PBMC populationsPre-prandial and 3 hours post-prandial on on test days through study completionDetermining changes in gene expression in pathways associated with RAGE signalling.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests6

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
1-Back TaskSecondary outcomeConductCognition
2-Back TaskSecondary outcomeConductCognition
Digit Span TestSecondary outcomeConductCognition
Stroop Color-Word TestSecondary outcomeConductCognition
Trail Making Test ASecondary outcomeConductCognition
Trail Making Test BSecondary outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03827239

GET https://conductscience.org/api/trials/v1/NCT03827239/registered