Trial · NCT03843671
Hyperbaric Radiation Sensitization of Head and Neck Cancers
NCT03843671, Phase 2, Unknown, National Baromedical Services
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Hyperbaric Radiation Sensitization of Head and Neck Cancers. Trials, record NCT03843671. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03843671
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Hyperbaric Radiation Sensitization of Head and Neck Cancers
- NCT number
- NCT03843671
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 400 participants, estimated
- Lead sponsor
- National Baromedical Services
- Conditions
- Squamous Cell Carcinoma of the Head and Neck
- Interventions
- Hyperbaric oxygen, Hyperbaric chamber
- First posted
- 2019-02-18
- Last updated
- 2019-02-18
- Other registries' IDs
- isrctn:ISRCTN93840508
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Progression free survival | Two years | Per blinded radiotherapy assessor |
| Primary | Relapse free survival | Two years | Per blinded radiotherapy assessor |
| Secondary | Overall survival | Two years | Per blinded radiotherapy assessor |
| Secondary | Incidence of acute hyperbaric complications; ear/sinus barotrauma, oxygen toxicity, myopia, confinement anxiety | At seven weeks from start of protocol, having completed 35 hyperbaric chamber exposures | Clinical and study record assessment by hyperbaric physician |
| Secondary | Incidence and degree of acute radiation toxicity | At seven weeks from start of protocol, having completed 35 radiotherapy treatments | Common Terminology Criteria Adverse Events version 5.0 |
| Secondary | Incidence and degree of late radiation tissue injury | Two years | Common Terminology Criteria Adverse Events version 5.0 and clinical assessment |
| Secondary | Hyperbaric protocol and radiotherapy dosing protocol compliance | Approximately 45 days after initiation of protocol | Assessed per Radiation Therapy Chair and hyperbaric oxygen physician per medical record review |
| Secondary | Subject quality of life: Rating scale | Two week post RT, then 3, 6, 12 & 24 months post radiotherapy | Functional Assessment of Cancer Therapy: Head and Neck version 4.0 $ Performance Status Scale for Head and Neck. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers24
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03843671
GET https://conductscience.org/api/trials/v1/NCT03843671/papers?page=2