Trial · NCT03846544
Double Pick up in Poor Prognosis Women
NCT03846544, Phase 4, Completed, CRG UZ Brussel; results first posted 2024-04-15
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Double Pick up in Poor Prognosis Women. Trials, record NCT03846544. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03846544
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Double Pick up in Poor Prognosis Women
- NCT number
- NCT03846544
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 48 participants, actual
- Lead sponsor
- CRG UZ Brussel
- Conditions
- Fertility Disorders
- Interventions
- Corifollitoropin alfa (CFA)-double pick up
- First posted
- 2019-02-19
- Last updated
- 2024-05-21
- Results first posted
- 2024-04-15
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of MII Oocytes Retrieved Between the Two Arms | 1 month | number of mature (or metaphase II, MII) oocytes retrieved during oocyte retrieval |
| Secondary | Number of Preovulatory Follicles | 1 month | number of follicles ≥11m on the day of final oocyte maturation trigger |
| Secondary | Number of Cumulus Oocyte Complexes (COCs) Retrieved | 1 month | number of COCs retrieved at oocyte retrieval |
| Secondary | Number of Oocytes Fertilized | 1 month | number of fertilized oocytes at day 1 after oocyte retrieval |
| Secondary | Total Number of Available Embryos | 1 month | number of available embryos at day 3 or day 5 after oocyte retrieval, good quality and therefore transferable |
| Secondary | Duration of Ovarian Stimulation | 1 month | number of days of ovarian stimulation |
| Secondary | Clinical Pregnancy Rates | 4 months | clinical pregnancy rate |
| Secondary | Live Birth Rates | 12 months | number of live births |
| Secondary | Cumulative Live Birth Rates | 24 months | defined as the first live birth following the transfer of fresh and subsequent frozen-thawed embryos |
Source ClinicalTrials.gov
Outcomes9
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of MII Oocytes Retrieved Between the Two Arms | 1 month | number of oocytes | MEAN | |
| SECONDARY | Number of Preovulatory Follicles | 1 month | number of follicles | MEAN | |
| SECONDARY | Number of Cumulus Oocyte Complexes (COCs) Retrieved | 1 month | number of oocytes | MEAN | |
| SECONDARY | Number of Oocytes Fertilized | 1 month | number of fertilized oocytes | MEAN | |
| SECONDARY | Total Number of Available Embryos | 1 month | number of embryos | MEAN | |
| SECONDARY | Duration of Ovarian Stimulation | 1 month | days | MEAN | |
| SECONDARY | Clinical Pregnancy Rates | 4 months | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Live Birth Rates | 12 months | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Cumulative Live Birth Rates | 24 months |
Source ClinicalTrials.gov
Results by group16
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of MII Oocytes Retrieved Between the Two Arms | Control Group | 4.1 | Standard Deviation 2.4 | number of oocytes | |
| Number of MII Oocytes Retrieved Between the Two Arms | Double Pick up Group | 3.0 | Standard Deviation 2.2 | number of oocytes | |
| Number of Preovulatory Follicles | Control Group | 5.4 | Standard Deviation 2.2 | number of follicles | |
| Number of Preovulatory Follicles | Double Pick up Group | 5.0 | Standard Deviation 1.6 | number of follicles | |
| Number of Cumulus Oocyte Complexes (COCs) Retrieved | Control Group | 5.3 | Standard Deviation 2.7 | number of oocytes | |
| Number of Cumulus Oocyte Complexes (COCs) Retrieved | Double Pick up Group | 3.3 | Standard Deviation 2.2 | number of oocytes | |
| Number of Oocytes Fertilized | Control Group | 3.7 | Standard Deviation 2.4 | number of fertilized oocytes | |
| Number of Oocytes Fertilized | Double Pick up Group | 2.3 | Standard Deviation 2.0 | number of fertilized oocytes | |
| Total Number of Available Embryos | Control Group | 1.5 | Standard Deviation 0.9 | number of embryos | |
| Total Number of Available Embryos | Double Pick up Group | 1.4 | Standard Deviation 1.3 | number of embryos |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Control Group | 24 | |
| Overall Study | STARTED | Double Pick up Group | 24 | |
| Overall Study | COMPLETED | Control Group | 23 | |
| Overall Study | COMPLETED | Double Pick up Group | 23 | |
| Overall Study | NOT COMPLETED | Control Group | 1 | |
| Overall Study | NOT COMPLETED | Double Pick up Group | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control Group | 0 | 24 |
| Total, all-cause mortality | Double Pick up Group | 0 | 24 |
| Total, other adverse events | Control Group | 0 | 24 |
| Total, other adverse events | Double Pick up Group | 0 | 24 |
| Total, serious adverse events | Control Group | 0 | 24 |
| Total, serious adverse events | Double Pick up Group | 0 | 24 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38199789 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons4
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Double Pick up Group vs Control Group: Clinical Pregnancy Rates | Trial comparisons |
| Double Pick up Group vs Control Group: deaths from any cause | Trial comparisons |
| Double Pick up Group vs Control Group: Live Birth Rates | Trial comparisons |
| Double Pick up Group vs Control Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03846544
GET https://conductscience.org/api/trials/v1/NCT03846544/registered