Trial · NCT03847545
Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique
NCT03847545, Not applicable, Completed, University of Southern Denmark
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique. Trials, record NCT03847545. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03847545
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Muscle Strain in Multiple Sclerosis Patients Measured by Ultrasound Speckle Tracking Technique
- NCT number
- NCT03847545
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 48 participants, actual
- Lead sponsor
- University of Southern Denmark
- Conditions
- Multiple Sclerosis
- Interventions
- Fampridine
- First posted
- 2019-02-20
- Last updated
- 2022-04-05
Source ClinicalTrials.gov
Registered outcomes42
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Gait Profile Score (GPS) - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in GPS. GPS is a summary measure of kinematic data. The GPS evaluates the overall quality of gait by comparing nine kinematic variables, described as Gait Variable Scores (GVS), relative to normative data. GPS is the root mean square (RMS) difference between the data of relevant kinematic variables of an individual patient and the averaged data from a reference group comprised of people without gait impairments. Originally we had registred that we would use the Gait Deviation Index (GDI). GDI is a unitless value from 0 to 100. It is based upon kinematic data and is an overall quantitative index that summarises the overall gait pathology into a single score for each patient by comparison with non-pathological gait. The GDI and GPS is highly correlated. We chose to use the GPS due to the inclusion of the GVS. |
| Secondary | Gait Variable Scores (GVS) - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in GVS. GVS refers to the Root Mean Square difference between the data of the following kinematic variables of an individual patient and the averaged data from a reference group comprised of people without gait impairments: Pelvic tilt, obliquity and rotation; hip flexion-extension, adduction-abduction, and rotation; knee flexion-extension; ankle dorsiflexion; and foot progression. |
| Secondary | Functional test - 6 Spot Step Test (SSST) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in time it takes the participant to walk through a rectangular area of 1x 5 meters while 5 cylinder blocks must be kicked out of 5 circles marked on the floor. |
| Secondary | Functional test - Timed 25 Footwalk (T25-FW) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in time it takes the participant to walk as safe and as quickly as possible through a straight clearly marked lane of 7.62 meters (25 feet). |
| Secondary | Functional test - 2-minute Walk Test (2MWT) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in distance that the participant is able to walk in 2 minutes. |
| Secondary | Walking speed - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in walking speed (m/s) |
| Secondary | Step length - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in step length (m) |
| Secondary | Step width - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in step width (m) |
| Secondary | Stride length - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in stride length (m) |
| Secondary | Cadence - (subgroup of 30 allocated to 3D gait analysis) | Baseline, 14 days (Change from baseline to 14 days follow-up) | Change in cadence (steps/min.) |
1 to 10 of 42Source ClinicalTrials.gov
See all 42 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03847545
GET https://conductscience.org/api/trials/v1/NCT03847545/registered?page=2