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Trial · NCT03854019

Results by group73

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Irritability as Assessed by The Irritability Scale.All Study Participants Pre-Randomization27.5Standard Deviation 5.8score on a scale
Irritability as Assessed by The Irritability ScaleDextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)18.7Standard Deviation 10.1score on a scale
Irritability as Assessed by The Irritability ScalePlacebo19.9Standard Deviation 9.4score on a scale
Behavioral Symptoms, as Assessed by the Hospital Anxiety and Depression Scale (HADS).All Study Participants Pre-Randomization16.7Standard Deviation 5.6score on a scale
Behavioral Symptoms, as Assessed by the Hospital Anxiety and Depression Scale (HADS).Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)10.6Standard Deviation 6.7score on a scale
Behavioral Symptoms, as Assessed by the Hospital Anxiety and Depression Scale (HADS).Placebo11.1Standard Deviation 8.3score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Severity Score.All Study Participants Pre-Randomization10.4Standard Deviation 4.2score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Severity Score.Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)8.2Standard Deviation 4.5score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Severity Score.Placebo8.6Standard Deviation 6.2score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Caregiver Distress.All Study Participants Pre-Randomization13.1Standard Deviation 6.5score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Caregiver Distress.Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)7.8Standard Deviation 5.2score on a scale
Behavioral Symptoms, as Assessed by the Neuropsychiatric Inventory-Questionnaire (NPI-Q) - Caregiver Distress.Placebo11.3Standard Deviation 7.4score on a scale
Behavioral Symptoms, as Assessed by the Problem Behaviors Assessment - Short Version (PBA-s). - Irritability/Aggression SubscaleAll Study Participants Pre-Randomization12.9Standard Deviation 7.2score on a scale
Behavioral Symptoms, as Assessed by the Problem Behaviors Assessment - Short Version (PBA-s) - Irritability/Aggression SubscaleDextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)7.6Standard Deviation 5.8score on a scale
Behavioral Symptoms, as Assessed by the Problem Behaviors Assessment - Short Version (PBA-s) - Irritability/Aggression SubscalePlacebo8.7Standard Deviation 5.7score on a scale
Motor Symptoms, as Assessed by the Total Motor Score (TMS) From the UHDRS.All Study Participants Pre-Randomization18.7Standard Deviation 11.8score on a scale
Motor Symptoms, as Assessed by the Total Motor Score (TMS) From the UHDRS.Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)19.3Standard Deviation 11.8score on a scale
Motor Symptoms, as Assessed by the Total Motor Score (TMS) From the UHDRS.Placebo18.7Standard Deviation 11.5score on a scale
Motor Symptoms, as Assessed by the Total Maximal Chorea (TMC).All Study Participants Pre-Randomization6.0Standard Deviation 3.8score on a scale
Motor Symptoms, as Assessed by the Total Maximal Chorea (TMC).Dextromethorphan/Quinidine 20mg/10mg (DM/Q 20mg/10mg)5.9Standard Deviation 4.3score on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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