Trial · NCT03880578
Quality of Life After Interventional Thyroid Treatment
NCT03880578, Completed, Klinikum Lüdenscheid; results first posted 2024-10-29
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Quality of Life After Interventional Thyroid Treatment. Trials, record NCT03880578. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03880578
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Quality of Life After Interventional Thyroid Treatment
- NCT number
- NCT03880578
- Status
- Completed
- Enrollment
- 101 participants, actual
- Lead sponsor
- Klinikum Lüdenscheid
- Conditions
- Thyroid; Deficiency, Quality of Life
- Interventions
- Levothyroxine Sodium
- First posted
- 2019-03-19
- Last updated
- 2024-10-29
- Results first posted
- 2024-10-29
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | ThyPRO Scale Scores (0-100, Higher Scores Indicating Worse Quality of Life) | 6 months | quality of life measured by a thyroid specific validated questionnaire |
| Secondary | Rate of Global Deiodinase Activity (SPINA-GD, See Reference Calculated Parameters) | 6 months | efficiency of converting T4 into T3 |
| Other | Serum Concentration of TSH | 6 months | TSH |
| Other | Serum Concentrations of FT3 and FT4 | 6 months | Thyroid hormones FT3, FT4 |
| Other | Thyroid Volume Measured by Ultrasound (ml) | 6 months | thyroid capacity |
Source ClinicalTrials.gov
Outcomes5
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | ThyPRO Scale Scores (0-100, Higher Scores Indicating Worse Quality of Life) | 6 months | score | MEAN | |
| SECONDARY | Rate of Global Deiodinase Activity (SPINA-GD, See Reference Calculated Parameters) | 6 months | nmol/s | MEAN | |
| OTHER_PRE_SPECIFIED | Serum Concentration of TSH | 6 months | mIU/L | MEAN | |
| OTHER_PRE_SPECIFIED | Serum Concentrations of FT3 and FT4 | 6 months | pmol/L | MEAN | |
| OTHER_PRE_SPECIFIED | Thyroid Volume Measured by Ultrasound (ml) | 6 months | ml | MEAN |
Source ClinicalTrials.gov
Results by group12
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| ThyPRO Scale Scores (0-100, Higher Scores Indicating Worse Quality of Life) | Control | 18.3 | Standard Deviation 10.8 | score | |
| ThyPRO Scale Scores (0-100, Higher Scores Indicating Worse Quality of Life) | Radioiodine | 19.9 | Standard Deviation 14.8 | score | |
| Rate of Global Deiodinase Activity (SPINA-GD, See Reference Calculated Parameters) | Control | 32.9 | Standard Deviation 5.03 | nmol/s | |
| Rate of Global Deiodinase Activity (SPINA-GD, See Reference Calculated Parameters) | Radioiodine | 32.2 | Standard Deviation 5.52 | nmol/s | |
| Serum Concentration of TSH | Control | 1.39 | Standard Deviation 0.63 | mIU/L | |
| Serum Concentration of TSH | Radioiodine | 2.34 | Standard Deviation 2.58 | mIU/L | |
| Serum Concentrations of FT3 and FT4 | Control | FT3 | 5.33 | Standard Deviation 0.60 | pmol/L |
| Serum Concentrations of FT3 and FT4 | Radioiodine | FT3 | 4.84 | Standard Deviation 0.65 | pmol/L |
| Serum Concentrations of FT3 and FT4 | Control | FT4 | 15.2 | Standard Deviation 2.13 | pmol/L |
| Serum Concentrations of FT3 and FT4 | Radioiodine | FT4 | 14.2 | Standard Deviation 2.38 | pmol/L |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 results by groupParticipant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Surgery (Withdrawn, Not Continuing Recruiting) | 0 | |
| Overall Study | STARTED | Radioiodine | 51 | |
| Overall Study | STARTED | Control | 50 | |
| Overall Study | 12 Months | Surgery (Withdrawn, Not Continuing Recruiting) | 0 | |
| Overall Study | 12 Months | Radioiodine | 14 | |
| Overall Study | 12 Months | Control | 19 | |
| Overall Study | COMPLETED | Surgery (Withdrawn, Not Continuing Recruiting) | 0 | |
| Overall Study | COMPLETED | Radioiodine | 47 | |
| Overall Study | COMPLETED | Control | 49 | |
| Overall Study | NOT COMPLETED | Surgery (Withdrawn, Not Continuing Recruiting) | 0 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control | 0 | 50 |
| Total, all-cause mortality | Radioiodine | 1 | 51 |
| Total, other adverse events | Control | 0 | 50 |
| Total, other adverse events | Radioiodine | 0 | 51 |
| Total, serious adverse events | Control | 0 | 50 |
| Total, serious adverse events | Radioiodine | 0 | 51 |
Source ClinicalTrials.gov
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Radioiodine vs Control: deaths from any cause | Trial comparisons |
| Radioiodine vs Control: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03880578
GET https://conductscience.org/api/trials/v1/NCT03880578/registered