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Trial · NCT03905694

Results by group54

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Time to Maximum Observed Plasma Concentration (Tmax) of LumasiranLumasiranMonth 243.73Full Range 1.67 to 10.3hours (h)
Elimination Half-life (t1/2beta) of LumasiranLumasiranDay 15.46Full Range 1.42 to 10.3hours (h)
Elimination Half-life (t1/2beta) of LumasiranLumasiranMonth 65.96Full Range 3.04 to 9hours (h)
Elimination Half-life (t1/2beta) of LumasiranLumasiranMonth 123.52Full Range 1.56 to 6.64hours (h)
Elimination Half-life (t1/2beta) of LumasiranLumasiranMonth 183.74Full Range 1.62 to 13.9hours (h)
Elimination Half-life (t1/2beta) of LumasiranLumasiranMonth 244.99Full Range 2.69 to 10.8hours (h)
Area Under the Concentration-time Curve From 0 to 24 Hours (AUC0-24) of LumasiranLumasiranDay 18050Geometric Coefficient of Variation 37.7hours*nanograms per milliliter (h*ng/mL)
Area Under the Concentration-time Curve From 0 to 24 Hours (AUC0-24) of LumasiranLumasiranMonth 68450Geometric Coefficient of Variation 41.1hours*nanograms per milliliter (h*ng/mL)
Area Under the Concentration-time Curve From 0 to 24 Hours (AUC0-24) of LumasiranLumasiranMonth 1210800Geometric Coefficient of Variation 39.3hours*nanograms per milliliter (h*ng/mL)
Area Under the Concentration-time Curve From 0 to 24 Hours (AUC0-24) of LumasiranLumasiranMonth 188420Geometric Coefficient of Variation 57.2hours*nanograms per milliliter (h*ng/mL)
Area Under the Concentration-time Curve From 0 to 24 Hours (AUC0-24) of LumasiranLumasiranMonth 247420Geometric Coefficient of Variation 61.6hours*nanograms per milliliter (h*ng/mL)
Area Under the Concentration-time Curve From 0 to Last Quantifiable Concentration (AUC0-last) of LumasiranLumasiranDay 17870Geometric Coefficient of Variation 33.4h*ng/mL
Area Under the Concentration-time Curve From 0 to Last Quantifiable Concentration (AUC0-last) of LumasiranLumasiranMonth 66620Geometric Coefficient of Variation 95.5h*ng/mL
Area Under the Concentration-time Curve From 0 to Last Quantifiable Concentration (AUC0-last) of LumasiranLumasiranMonth 128480Geometric Coefficient of Variation 76.1h*ng/mL
Area Under the Concentration-time Curve From 0 to Last Quantifiable Concentration (AUC0-last) of LumasiranLumasiranMonth 185770Geometric Coefficient of Variation 155.0h*ng/mL
Area Under the Concentration-time Curve From 0 to Last Quantifiable Concentration (AUC0-last) of LumasiranLumasiranMonth 247100Geometric Coefficient of Variation 80.0h*ng/mL
Area Under the Concentration-time Curve From 0 to Infinity (AUC0-infinity) of LumasiranLumasiranDay 19180Geometric Coefficient of Variation 31.7h*ng/mL
Area Under the Concentration-time Curve From 0 to Infinity (AUC0-infinity) of LumasiranLumasiranMonth 68840Geometric Coefficient of Variation 40.9h*ng/mL
Area Under the Concentration-time Curve From 0 to Infinity (AUC0-infinity) of LumasiranLumasiranMonth 1211900Geometric Coefficient of Variation 29.2h*ng/mL
Area Under the Concentration-time Curve From 0 to Infinity (AUC0-infinity) of LumasiranLumasiranMonth 1811600Geometric Coefficient of Variation 48.6h*ng/mL

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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