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Trial · NCT03920618

Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF

NCT03920618, Not applicable, Recruiting, Third Affiliated Hospital, Sun Yat-Sen University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF. Trials, record NCT03920618. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03920618

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF
NCT number
NCT03920618
Status
Recruiting
Phases
Not applicable
Enrollment
150 participants, estimated
Lead sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Conditions
Hepatitis B, Acute-On-Chronic Liver Failure
Interventions
Entecavir, Tenofovir Disoproxil Fumarate, Tenofovir Alafenamide
First posted
2019-04-19
Last updated
2024-11-29

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySurvival rate in the follow-up144 weekWhether patients will survive after treatment is observed in the follow-up.
SecondaryModel for end-stage liver disease (MELD) score is recorded after treatment0 week, 4 week, 8 week, 12 week, 24 week, 48 week, 72 week,144 week
The calculation of model for end-stage liver disease (MELD) score is: R=0.378ln\[serum total bilirubin (mg/dl)\]+1.12ln(prothrombin time international normalized ratio)+0.95ln\[serum creatinin(mg/dl)\]+0.64. The higher the MELD score, the higher the mortality rate. MELD score is recorded after treatment.
SecondaryRatio of patients with undetectable hepatitis b virus DNA after treatment4 week, 8 week, 12 week, 24 week, 48 week, 72 week,144 weekHepatitis b virus DNA would be tested to know the ratio of patients with undetectable hepatitis b virus DNA at 7 time points after treatment.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
39958923DERIVED

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT03920618

GET https://conductscience.org/api/trials/v1/NCT03920618/registered