Trial · NCT03923374
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
NCT03923374, Recruiting, Senthil Sadhasivam
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes. Trials, record NCT03923374. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03923374
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
- NCT number
- NCT03923374
- Status
- Recruiting
- Enrollment
- 600 participants, estimated
- Lead sponsor
- Senthil Sadhasivam
- Conditions
- Opioid-use Disorder, Opioid Use, Unspecified, Buprenorphine Dependence
- Interventions
- Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws
- First posted
- 2019-04-22
- Last updated
- 2025-12-18
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of opioid misuse severity using assessments | 5 years | Incidence of opioid misuse severity and buprenorphine treatment response will be assessed by the treating physician using assessments such as Who Assist, TCU Motform, Adverse Childhood Experience Assessment, Ham-A and Ham-D. |
| Primary | Pharmacological treatment for neonatal abstinence syndrome | 5 years | Incidence of Neonatal Abstinence Syndrome and need for pharmacological treatment. |
| Secondary | Incidence of adverse effects of buprenorphine using MRI | 5 years | Incidence of adverse effects of buprenorphine use on fetal and placental changes using MRI. |
| Secondary | Concentration of long-term neurodevelopmental outcomes using assessments | 5 years | Concentration of long-term neurodevelopmental outcomes in neonates using the Ages and Stages Questionnaire and the Baileys follow-up assessment. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01HD096800 | Effects of Opioid Use Disorder in Pregnancy on Long-Term Maternal and Child Outcomes | SADHASIVAM, SENTHILKUMAR | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2018 to 2022 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03923374
GET https://conductscience.org/api/trials/v1/NCT03923374/registered