Trial · NCT03943979
Pilot Study of an Intervention Involving Cognitive Training and tDCS in Morbidly Obese Subjects
NCT03943979, Phase 2, Completed, Parc de Salut Mar
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Pilot Study of an Intervention Involving Cognitive Training and tDCS in Morbidly Obese Subjects. Trials, record NCT03943979. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03943979
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Pilot Study of an Intervention Involving Cognitive Training and tDCS in Morbidly Obese Subjects
- NCT number
- NCT03943979
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 18 participants, actual
- Lead sponsor
- Parc de Salut Mar
- Conditions
- Obesity, Morbid, Obesity (BMI > 35) and Diabetes Mellitus, Obesity (BMI > 35) and High Blood Pressure, Obesity (BMI > 35) and Dyslipemia
- Interventions
- Cognitive Training, transcranial Direct-Current Stimulation (tDCS)
- First posted
- 2019-05-09
- Last updated
- 2019-05-09
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in food intake | 4 consecutive days during the week before starting the treatment; 4 consecutive days during the week of treatment; | Changes in food consumption (medium kcal intake ) from baseline to the end of the treatment measured by 4-day food registers during the week before starting the treatment and during the 4 days of treatment. The dietary records were checked by a nutritionist and analyzed through the software PCN Pro 1.0. |
| Primary | Stability of changes in food intake | 4 consecutive days during the week before starting the treatment and 4 consecutive days during the week after finishing the treatment | Changes in food consumption (medium kcal intake ) from baseline to the follow-up assessment measured by 4-day food registers during the week before starting the treatment and the week after finishing the treatment. The dietary records were checked by a nutritionist and analyzed through the software PCN Pro 1.0. |
| Secondary | Change in electroencephalogram (EEG) power and coherence | Every training session (4 consecutive days), 3 minutes before starting the training session and 3 minutes after finishing the training. | EEG was recorded before and after tCS/sham using a Starstim device (Neuroelectrics), same electrode positions as for the stimulation with a sampling frequency of 500 S/s . Electrode impedance: below 10kΩ; electrical reference placed at the right earlobe. EEG data was analyzed offline by means of customized Matlab code (MathWorks Inc. Natick, MA, USA). Data was split into 1s non-overlapping epochs (epochs with amplitudes \>50 μV were rejected). EEG-metrics extracted: EEG-power and coherence. To compute EEG power, the power spectral density (PSD) was estimated for each epoch. Band Power was computed for the bands θ=\[4,8 Hz\], α=\[8,13 Hz\] β=\[13,25 Hz\], γ=\[30, 45 Hz\] and broadband=\[4-45Hz\] by integrating the PSD within the band frequency limits. Functional connectivity was estimated by means of coherence by the Welch method averaged over all electrodes. Frontal asymmetry (FA) computed as follows: log(avg(AF4 F4 F8 FC6))-log(avg(AF3 F3 F7 FC5); FA\<0 reflects dominance of left-hemisphere |
| Secondary | Change in Body Mass Index (BMI) | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Change in BMI. BMI calculation: body weight divided by the square of the body height (expressed in units of kg/m2). Weight and height measures were taken by a nurse. |
| Secondary | Change in endocannabinoids (and related compounds) plasmatic concentrations. | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Change in endocannabinoids and related compounds (acylglycerols and fatty acid N-acylethanolamides) as measured in plasmatic concentrations and quantified by LC/MS-MS by a previously validated method (Pastor et al. 2014). |
| Secondary | Change in hormonal measurements : Leptin and adiponectin plasmatic/serum concentrations | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Measurement of change in hormones regulating the appetite and energic homeostasis of secretion in fatty tissues. |
| Secondary | Change in neuropsychological test: Intra-extra dimension (IED-CANTAB Cambridge Cognition) | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Executive functions: flexibility |
| Secondary | Change in neuropsychological test: Stroop Colours and Words test (SCWT, Golden C.J., 1978; Stroop, 1935) | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Executive functions: inhibition |
| Secondary | Change in neuropsychological test: Iowa Gambling Task (IGT, Bechara et al., 1994, 2002) | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Executive functions: decision-making, risky behaviour. |
| Secondary | Change in neuropsychological test: Spatial Span (SSP; CANTAB Cambridge Cognition) | One day during the week before starting the training (pre-treatment) and the 1 day after finishing the treatment (post-treatment) | Executive functions: working memory |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers12
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests6
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Continuous Performance Test | Secondary outcome | ConductCognition |
| Iowa Gambling Lite | Secondary outcome | ConductCognition |
| Simple Reaction Time | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Symbol Coding | Secondary outcome | ConductCognition |
| Tower Planning | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03943979
GET https://conductscience.org/api/trials/v1/NCT03943979/registered