Trial · NCT03963544
Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST)
NCT03963544, Completed, Institut Bergonié; results first posted 2025-12-10
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST). Trials, record NCT03963544. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT03963544
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Patterns of Care and Outcomes of Patients With METAstatic Gastrointestinal Stromal Tumors (METAGIST)
- NCT number
- NCT03963544
- Status
- Completed
- Enrollment
- 492 participants, actual
- Lead sponsor
- Institut Bergonié
- Conditions
- Gastro Intestinal Stromal Tumor
- Interventions
- oral tyrosine-kinase inhibitors (TKI) of KIT and PDGFR as per recommendations
- First posted
- 2019-05-24
- Last updated
- 2025-12-10
- Results first posted
- 2025-12-10
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to Next Treatment (TNT) | 10 years | time from the systemic treatment onset to the next treatment or death due to any cause, whichever came first. |
| Primary | Overall Survival (OS) Time | 10 years | the interval between the diagnosis of metastatic disease or the first-line systemic therapy onset and the time of death. |
| Secondary | Treatment With a Systemic Therapy | At diagnosis of metastatic disease | Proportion of metastatic patients treated with a systemic therapy |
| Secondary | Proportion of Participants Included in a Clinical Trial | 5 years | Proportion of participants included in a clinical trial (other than the present study) during the course of their metastatic disease |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Time to Next Treatment (TNT) | 10 years | Participants who received systemic treatment | months | MEDIAN |
| PRIMARY | Overall Survival (OS) Time | 10 years | months | MEDIAN | |
| SECONDARY | Treatment With a Systemic Therapy | At diagnosis of metastatic disease | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Proportion of Participants Included in a Clinical Trial | 5 years | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Time to Next Treatment (TNT) | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 26.7 | 95% Confidence Interval 23.4 to 32.3 | months | |
| Overall Survival (OS) Time | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 83.4 | 95% Confidence Interval 72.7 to 97.9 | months | |
| Treatment With a Systemic Therapy | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 461 | Participants | ||
| Proportion of Participants Included in a Clinical Trial | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 269 | Participants |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 492 | |
| Overall Study | COMPLETED | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 492 | |
| Overall Study | NOT COMPLETED | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 221 | 492 |
| Total, other adverse events | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 0 | 0 |
| Total, serious adverse events | Participants With Metastatic Gastrointestinal Stromal Tumors (GIST) | 0 | 0 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 37686582 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT03963544
GET https://conductscience.org/api/trials/v1/NCT03963544/registered