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Trial · NCT03985943

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Participants With an Investigator's Global Assessment (IGA) Success (IGA of 0 or 1 and a More Than Equal to [>=] 2-point Reduction): Intent-To-Treat (ITT) PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo24.6percentage of participants
Percentage of Participants With an Investigator's Global Assessment (IGA) Success (IGA of 0 or 1 and a More Than Equal to [>=] 2-point Reduction): Intent-To-Treat (ITT) PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg35.6percentage of participants
Percentage of Participants With an Investigator's Global Assessment (IGA) Success (IGA of 0 or 1 and a >= 2-point Reduction): Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo21.4percentage of participants
Percentage of Participants With an Investigator's Global Assessment (IGA) Success (IGA of 0 or 1 and a >= 2-point Reduction): Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg35.5percentage of participants
Percentage of Participants With >=75% Improvement in Eczema Area and Severity Index (EASI-75) at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo29.0percentage of participants
Percentage of Participants With >=75% Improvement in Eczema Area and Severity Index (EASI-75) at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg43.5percentage of participants
Percentage of Participants With >=75% Improvement in Eczema Area and Severity Index (EASI-75) at 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo23.8percentage of participants
Percentage of Participants With >=75% Improvement in Eczema Area and Severity Index (EASI-75) at 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg41.6percentage of participants
Percentage of Participants With Improvement of >=4 Points in Weekly Average Peak Pruritus Numeric Rating Scale (PP NRS) at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo17.8percentage of participants
Percentage of Participants With Improvement of >=4 Points in Weekly Average Peak Pruritus Numeric Rating Scale (PP NRS) at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg42.7percentage of participants
Percentage of Participants With Improvement of >=4 Points in Weekly Average Peak Pruritus Numeric Rating Scale (PP NRS) at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo18.6percentage of participants
Percentage of Participants With Improvement of >=4 Points in Weekly Average Peak Pruritus Numeric Rating Scale (PP NRS) at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg46.1percentage of participants
Percentage of Participants With <2 Points in Weekly Average PP NRS at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo11.2percentage of participants
Percentage of Participants With <2 Points in Weekly Average PP NRS at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg30.6percentage of participants
Percentage of Participants With <2 Points in Weekly Average PP NRS at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo7.6percentage of participants
Percentage of Participants With <2 Points in Weekly Average PP NRS at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg27.8percentage of participants
Percentage of Participants With an Improvement of Sleep Disturbance Numeric Rating Scale (SD NRS) >=4 at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo19.9percentage of subjects
Percentage of Participants With an Improvement of Sleep Disturbance Numeric Rating Scale (SD NRS) >=4 at Week 16: ITT PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg37.9percentage of subjects
Percentage of Participants With an Improvement of Sleep Disturbance Numeric Rating Scale (SD NRS) >=4 at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Placebo22.4percentage of participants
Percentage of Participants With an Improvement of Sleep Disturbance Numeric Rating Scale (SD NRS) >=4 at Week 16: Severe Pruritus PopulationInitial Treatment Period (Baseline - Week 16 Predose): Nemolizumab 30 mg42.1percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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