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Trial · NCT03990363

Results by group56

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)High Dose Versus Allopurinol1.02395% Confidence Interval 0.9773 to 1.070mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Interemdiate Dose Versus Allopurinol0.985995% Confidence Interval 0.9429 to 1.031mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Low Dose Versus Allopurinol1.02495% Confidence Interval 0.9786 to 1.071mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Allopurinol Versus Placebo0.986895% Confidence Interval 0.9436 to 1.032mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)High Dose0.9809Geometric Coefficient of Variation 20.09mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)Intermediate Dose0.9454Geometric Coefficient of Variation 21.24mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)Low Dose0.9613Geometric Coefficient of Variation 17.59mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)Switch Dose PA51.101Geometric Coefficient of Variation 27.23mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)Allopurinol0.9593Geometric Coefficient of Variation 23.36mL/min/1.73 m²
Estimated Glomerular Filtration Rate (eGFR) (mL/Min/1.73 m²) Change From Baseline at 12 Months (Visit 10)Placebo0.9469Geometric Coefficient of Variation 23.33mL/min/1.73 m²
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)High Dose Versus Placebo0.988895% Confidence Interval 0.9523 to 1.027Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Intermediate Dose Versus Placebo1.02395% Confidence Interval 0.9857 to 1.062Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Low Dose Versus Placebo0.990195% Confidence Interval 0.9538 to 1.028Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)High Dose Versus Allopurinol0.980195% Confidence Interval 0.9437 to 1.018Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Interemdiate Dose Versus Allopurinol1.01495% Confidence Interval 0.9770 to 1.053Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Low Dose Versus Allopurinol0.981495% Confidence Interval 0.9452 to 1.019Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 6 Months (V8), Repeated Measures Mixed Model (MMRM)Allopurinol Versus Placebo1.00995% Confidence Interval 0.9718 to 1.047Geometric Mean Ratio
S-creatinine (mg/dL) Change From Baseline at 12 Months (Visit 10)High Dose1.011Geometric Coefficient of Variation 18.57mg/dL
S-creatinine (mg/dL) Change From Baseline at 12 Months (Visit 10)Intermediate Dose1.038Geometric Coefficient of Variation 18.37mg/dL
S-creatinine (mg/dL) Change From Baseline at 12 Months (Visit 10)Low Dose1.026Geometric Coefficient of Variation 17.15mg/dL

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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