Trial · NCT04008511
Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal Cancer
NCT04008511, Phase 1, Phase 2, Unknown, China Medical University, China
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal Cancer. Trials, record NCT04008511. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04008511
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Regorafenib and XELOX as 2nd Line Treatment in Metastatic Colorectal Cancer
- NCT number
- NCT04008511
- Status
- Unknown
- Phases
- Phase 1, Phase 2
- Enrollment
- 54 participants, estimated
- Lead sponsor
- China Medical University, China
- Conditions
- Metastatic Colorectal Cancer
- Interventions
- Regorafenib, Regorafenib, Capecitabine, Oxaliplatin
- First posted
- 2019-07-05
- Last updated
- 2019-07-05
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Maximum tolerated dose (MTD) | 6 weeks | The MTD is defined as the highest dose that can be given so that toxicity probability is below the target toxicity PT=30%. |
| Primary | Progression-free survival (PFS) | 1 year | PFS is defined as the time (days) from start of study treatment to date of first observed disease progression (investigator's radiological or clinical assessment) or death due to any cause, if death occurs before progression is documented. |
| Primary | Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 | 3 years | Safety and tolerability |
| Secondary | Disease control rate (DCR) | 3 years | o DCR is defined as the percentage of patients, whose overall best response was not progressive disease. |
| Secondary | Overall response rate (ORR) | 3 years | o ORR is defined as the percentage of patients with complete response (CR) or partial response (PR). |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04008511
GET https://conductscience.org/api/trials/v1/NCT04008511/registered