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Trial · NCT04011748

Clinical Application of Stem Cell Educator Therapy in Alopecia Areata

NCT04011748, Phase 2, Active not recruiting, Throne Biotechnologies Inc.

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Clinical Application of Stem Cell Educator Therapy in Alopecia Areata. Trials, record NCT04011748. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04011748

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Clinical Application of Stem Cell Educator Therapy in Alopecia Areata
NCT number
NCT04011748
Status
Active not recruiting
Phases
Phase 2
Enrollment
20 participants, estimated
Lead sponsor
Throne Biotechnologies Inc.
Conditions
Alopecia Areata, Alopecia Totalis, Alopecia Universalis
Interventions
Stem Cell Educator therapy
First posted
2019-07-08
Last updated
2026-09-30

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryThe percentage change in scalp hair growth.Hair regrowth will be evaluated at different time points post receiving Stem Cell Educator therapy in 1, 3, and 6 months.The primary endpoint was the percentage change in scalp hair growth, measured with the Severity of Alopecia Tool (SALT) score.
SecondaryFeasibility of SCE therapy6 monthsThe feasibility will be determined by the number of patients who were unable to complete SCE Therapy.
SecondaryPreliminary efficacy of SCE therapy6 monthsThis will be determined by the duration of maintaining hair growth following SCE therapy.
SecondaryEfficacy of modulation of autoimmune-related memory T-cell markers6 months
Measurements of immune markers' changes will be preformed by flow cytometry such as CD8+CD45RO+CCR7- effector memory T cells. Peripheral blood mononuclear cells (PBMC) will be collected at 1, 3, 6 month post the SCE therapy.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers4

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
22233865RESULTPubMed
22833322RESULTPubMed
25896390RESULTPubMed
35108619BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04011748

GET https://conductscience.org/api/trials/v1/NCT04011748/registered