Trial · NCT04022941
Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.
NCT04022941, Not applicable, Completed, Institute of Liver and Biliary Sciences, India
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease. Trials, record NCT04022941. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04022941
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of Sodium Benzoate in the Management of Hyperammonemia in Infants, Children and Adolescent With Chronic Liver Disease.
- NCT number
- NCT04022941
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 108 participants, actual
- Lead sponsor
- Institute of Liver and Biliary Sciences, India
- Conditions
- Chronic Liver Disease
- Interventions
- Sodium Benzoate, Powdered table sugar as palcebo
- First posted
- 2019-07-17
- Last updated
- 2019-07-17
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in the blood ammonia levels at 5 days of starting therapy in both groups. | Day 5 | |
| Secondary | Change in the grading of Hepatic Encephalopathy in both groups. | Day 28 | |
| Secondary | Change in the grading of Hepatic Encephalopathy in both groups. | Day 90 | |
| Secondary | Proportion of children with worsening ascites in both groups. | Day 28 | |
| Secondary | Proportion of children with worsening ascites in both groups. | Day 90 | |
| Secondary | Proportion of children with hypernatremia in both groups. | Day 28 | |
| Secondary | Proportion of children with hypernatremia in both groups. | Day 90 | |
| Secondary | Proportion of children with metabolic acidosis in both groups. | Day 28 | |
| Secondary | Proportion of children with metabolic acidosis in both groups. | Day 90 | |
| Secondary | Duration of hospital stay in both groups. | Day 28 |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04022941
GET https://conductscience.org/api/trials/v1/NCT04022941/registered