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Trial · NCT04026113

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Functional Constipation (FC) Participants: Change From Baseline in 12-week SBM (Spontaneous Bowel Movement) Frequency Rate (SBMs/Week) During the Study Intervention PeriodFC Participants: Placebo1.050Standard Error 0.187SBMs
Functional Constipation (FC) Participants: Change From Baseline in 12-week SBM (Spontaneous Bowel Movement) Frequency Rate (SBMs/Week) During the Study Intervention PeriodFC Participants: Linaclotide 72 μg2.220Standard Error 0.187SBMs
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks APS (Abdominal Pain and SBM) + 2 Responder RateIBS-C Participants: Linaclotide 145 μg22.6percentage of participants
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks APS (Abdominal Pain and SBM) + 2 Responder RateIBS-C Participants: Linaclotide 290 μg23.4percentage of participants
Functional Constipation (FC) Participants: Change From Baseline in 12-week Stool Consistency During the Study Intervention PeriodFC Participants: Placebo0.685Standard Error 0.078units on a scale
Functional Constipation (FC) Participants: Change From Baseline in 12-week Stool Consistency During the Study Intervention PeriodFC Participants: Linaclotide 72 μg1.108Standard Error 0.077units on a scale
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week SBM Frequency Rate (SBMs/Week) During the Study Intervention PeriodIBS-C Participants: Linaclotide 145 μg2.347Standard Deviation 3.3335SBMs/week
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week SBM Frequency Rate (SBMs/Week) During the Study Intervention PeriodIBS-C Participants: Linaclotide 290 μg2.747Standard Deviation 2.8861SBMs/week
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week Abdominal Pain During the Study Intervention PeriodIBS-C Participants: Linaclotide 145 μg-0.837Standard Deviation 0.9313units on a scale
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week Abdominal Pain During the Study Intervention PeriodIBS-C Participants: Linaclotide 290 μg-0.837Standard Deviation 0.8809units on a scale
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week Stool Consistency During the Study Intervention PeriodIBS-C Participants: Linaclotide 145 μg0.979Standard Deviation 1.2900units on a scale
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: Change From Baseline in 12-week Stool Consistency During the Study Intervention PeriodIBS-C Participants: Linaclotide 290 μg1.358Standard Deviation 1.1288units on a scale
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks SBM + 2 Responder RateIBS-C Participants: Linaclotide 145 μg30.2percentage of participants
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks SBM + 2 Responder RateIBS-C Participants: Linaclotide 290 μg29.8percentage of participants
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks Abdominal Pain ResponderIBS-C Participants: Linaclotide 145 μg49.1percentage of participants
Irritable Bowel Syndrome With Constipation (IBS-C) Participants: 6/12 Weeks Abdominal Pain ResponderIBS-C Participants: Linaclotide 290 μg42.6percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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