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Trial · NCT04042623

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIncidence of Adverse Events (AEs)14 weeksMeasured by the number of patients with AEs
PrimaryThe Effect of AVB-S6-500 on Change From Baseline to End of Treatment in 24-hour Urine Protein Excretion (UPE) in g/Day.12 weeks
PrimaryThe Effect of AVB-S6-500 on Change From Baseline to End of Treatment in 24-hour Urine Protein Excretion (UPE) in g/Day in the Subset of Patients With Baseline High Proteinuria.12 weeks
PrimaryThe Effect of AVB-S6-500 on Proportion of Patients With Urinary Protein Equivalent of < 1 g/24 Hours at End of Treatment12 weeks
PrimaryThe Effect of AVB-S6-500 on Proportion of Patients Who Had at Least a Decrease of 0.5 g/Day Proteinuria From Baseline to End of Treatment.12 weeks
PrimaryThe Effect of AVB-S6-500 on Change From Baseline to End of Treatment in Urine Albumin/Creatinine Ratios (uACRs).12 weeks
PrimaryThe Effect of AVB-S6-500 on Change From Baseline to End of Treatment in Estimated Glomerular Filtration Rate (eGFR).12 weeks
SecondaryIncidence of Anti-drug Antibody (ADA)14 weeksThe number of participants with anti-AVB-S6-500 antibodies
SecondaryTiters of Anti-AVB-S6-500 Antibodies14 weeks
SecondaryApparent Terminal Half-life (t1/2) of AVB-S6-50012 weeks
SecondaryMaximum Observed Plasma Concentration of AVB-S6-500 (Cmax)12 weeks
SecondaryArea Under Time-concentration Curve (AUC)12 weeks
SecondaryTime of Maximum Observed AVB-S6-500 Concentration (Tmax)12 weeks

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT04042623/registered