Trial · NCT04049552
RAPA-Keloid Study of Keloid Regression
NCT04049552, Early phase 1, Completed, The University of Texas Health Science Center at San Antonio; results first posted 2020-12-28
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. RAPA-Keloid Study of Keloid Regression. Trials, record NCT04049552. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04049552
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- RAPA-Keloid Study of Keloid Regression
- NCT number
- NCT04049552
- Status
- Completed
- Phases
- Early phase 1
- Enrollment
- 4 participants, actual
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Conditions
- Keloid
- Interventions
- Rapamycin 8% Ointment, Placebo
- First posted
- 2019-08-08
- Last updated
- 2021-09-29
- Results first posted
- 2020-12-28
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Keloid Surface Area | Baseline to 6 months | Measurement of surface area of keloid |
| Secondary | Change in Keloid Height | Baseline to 6 months | Measurement of height of keloid |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Keloid Surface Area | Baseline to 6 months | cm2 | MEAN | |
| SECONDARY | Change in Keloid Height | Baseline to 6 months | millimeters | MEAN |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Keloid Surface Area | RAPA Intervention | 0.455 | Full Range 0.131 to 0.735 | cm2 | |
| Change in Keloid Surface Area | Placebo | -0.039 | Full Range -0.09 to -0.0075 | cm2 | |
| Change in Keloid Height | RAPA Intervention | Baseline | 1.5 | Full Range 1.08 to 2.04 | millimeters |
| Change in Keloid Height | Placebo | Baseline | 1.55 | Full Range 1.29 to 1.93 | millimeters |
| Change in Keloid Height | RAPA Intervention | 6 months | 1.056 | Full Range 0.4 to 1.54 | millimeters |
| Change in Keloid Height | Placebo | 6 months | 0.93 | Full Range 0.33 to 1.30 | millimeters |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Overall Study Participants | 4 | 8 |
| Overall Study | COMPLETED | Overall Study Participants | 3 | 6 |
| Overall Study | NOT COMPLETED | Overall Study Participants | 1 | 2 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | RAPA Intervention | 0 | 3 |
| Total, all-cause mortality | Placebo | 0 | 3 |
| Total, other adverse events | RAPA Intervention | 0 | 3 |
| Total, other adverse events | Placebo | 0 | 3 |
| Total, serious adverse events | RAPA Intervention | 0 | 3 |
| Total, serious adverse events | Placebo | 0 | 3 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| RAPA Intervention vs Placebo: deaths from any cause | Trial comparisons |
| RAPA Intervention vs Placebo: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04049552
GET https://conductscience.org/api/trials/v1/NCT04049552/registered