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Trial · NCT04062890

Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance

NCT04062890, Phase 2, Withdrawn, University of Arizona

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance. Trials, record NCT04062890. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04062890

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Inhibiting GABA Transaminase to Relieve Obesity Induced Hyperinsulinemia and Insulin Resistance
NCT number
NCT04062890
Status
Withdrawn
Phases
Phase 2
Enrollment
0 participants, actual
Lead sponsor
University of Arizona
Conditions
Hyperinsulinism, Insulin Resistance, Insulin Sensitivity, Glucose Intolerance, Hypertension
Interventions
Vigabatrin Pill, Placebo oral tablet
First posted
2019-08-20
Last updated
2025-07-30

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryFasted serum glucose and insulin3 weeks after treatment initiationOvernight fasted serum glucose and insulin
PrimaryGlucose Clearance3 weeks after treatment initiationClearance of glucose during an oral glucose tolerance test
PrimaryInsulin Sensitivity24 days after treatment initiationInsulin sensitivity measured by glucose infusion rate required to maintain euglycemia during a hyperinsulinemic clamp
PrimaryBlood Pressure21 days after treatment initiationMeasure basal blood pressure both before and 21 days after treatment initiation

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04062890

GET https://conductscience.org/api/trials/v1/NCT04062890/registered