Trial · NCT04098991
Improving White Matter Integrity With Thyroid Hormone
NCT04098991, Completed, University of Illinois Chicago
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Improving White Matter Integrity With Thyroid Hormone. Trials, record NCT04098991. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04098991
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Improving White Matter Integrity With Thyroid Hormone
- NCT number
- NCT04098991
- Status
- Completed
- Enrollment
- 5 participants, actual
- Lead sponsor
- University of Illinois Chicago
- Conditions
- Hypothyroidism
- Interventions
- Levothyroxine
- First posted
- 2019-09-23
- Last updated
- 2020-04-10
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | High Angular Diffusion Tensor Imaging | 6 months | Change in baseline white matter track integrity at 3 months and 6 months |
| Primary | Multi-Component Relaxometry | 6 months | Change in baseline white matter track integrity at 3 months and 6 months |
| Secondary | Patient Health Questionaire | Collected at Baseline, 3 month follow-up, 6 month follow-up | Self-report measure of depression severity, Items are summed (Not at all = 0; Several days = 1; More than half the days = 2; Nearly every day = 3), yielding a score from 0 to 27 |
| Secondary | NIH Toolbox : Dimensional Change Card Sort Test | Collected at Baseline, 3 month follow-up, 6 month follow-up | Behavioral measures of executive functioning |
| Secondary | NIH Toolbox : Pattern Comparison Processing Speed Test | Collected at Baseline, 3 month follow-up, 6 month follow-up | Behavioral measures of processing-speed measure |
| Secondary | NIH Toolbox : Flanker Inhibitory Control and Attention Test | Collected at Baseline, 3 month follow-up, 6 month follow-up | Behavioral measures of attention |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R21NS095723 | Improving white matter integrity with thyroid hormone | AJILORE, OLUSOLA A. | UNIVERSITY OF ILLINOIS AT CHICAGO | NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE | 2016 to 2017 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Dimensional Change Card Sort | Secondary outcome | ConductCognition |
| Pattern and Letter Comparison | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04098991
GET https://conductscience.org/api/trials/v1/NCT04098991/registered