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Trial · NCT04142190

Registered outcomes18

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryTime of pronuclei disappearance16-18 hours after fertilizationTime of pronuclei disappearance in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryTwo discrete cells26-28 hours after fertilizationThe first observation of two discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryThree discrete cells28-44 hours after fertilizationThe first observation of three discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryFour discrete cells44-45 hours after fertilizationThe first observation of four discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryFive discrete cells44-68 hours after fertilizationThe first observation of five discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimarySix discrete cells44-68 hours after fertilizationThe first observation of six discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimarySeven discrete cells44-68 hours after fertilizationThe first observation of seven discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryEight discrete cells68-69 hours after fertilizationThe first observation of eight discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryNine discrete cells69-92 hours after fertilizationThe first observation of nine discrete cells in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
PrimaryMorula stage92 hours after fertilizationEnd of the compaction process; when observable compaction is complete in embryos of patients stimulated with ELONVA versus embryos of patients stimulated with PUREGON
SecondaryNumber of oocytes retrievedNumber of oocytes retrieved will be evaluated after one treatment cycle (each cycle is between 28 and 35 days)The influence of ELONVA versus PUREGON on the number of oocytes retrieved will be assessed.
SecondaryStage of oocyte developmentStage of oocytes retrieved will be evaluated after one treatment cycle (each cycle is between 28 and 35 days)The influence of ELONVA versus PUREGON on the maturity stage of oocytes (germinal vesicle, metaphase I (MI) or MII phase) retrieved will be assessed.
SecondaryFertilized oocytesNumber of fertilized oocytes will be evaluated after one treatment cycle (each cycle is between 28 and 35 days)The influence of ELONVA versus PUREGON on the number of fertilized oocytes will be assessed.
SecondaryEmbryo gradingThe quality of embryos will be evaluated after one treatment cycle (each cycle is between 28 and 35 days)
The influence of ELONVA versus PUREGON on embryo grading (Istanbul consensus criteria) will be assessed. The grading consists of assessment of cell number, fragmentation, multinucleation, cell size, cytoplasmic granularity, membrane appearance, and the presence of vacuoles).
SecondaryBiochemical pregnancy (measurement of beta hCG)Biochemical pregnancies will be evaluated after successful implantation (1 week after embryo transfer)The influence of Elonva versus Puregon on the number of biochemical pregnancies will be assessed.
SecondaryLife birthLife births will be evaluated after successful pregnancy (9 moths after embryo transfer)The influence of Elonva versus Puregon on the number of life births will be assessed.
SecondaryWeight (kilograms)Weight of the newborn will be evaluated after birth (9 moths after embryo transfer)The influence of Elonva versus Puregon on the weight of the newborn will be assessed.
SecondaryHeight (centimeters)Height of the newborn will be evaluated after birth (9 moths after embryo transfer)The influence of Elonva versus Puregon on the height of the newborn will be assessed.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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