Underlying Causes and Related Factors, and Rehabilitation Approaches
NCT04142853, Not applicable, Completed, Hasselt University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Underlying Causes and Related Factors, and Rehabilitation Approaches | ClinicalTrials.gov |
| NCT number | NCT04142853 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 40 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Hasselt University | ClinicalTrials.gov |
| Conditions | Multiple Sclerosis | ClinicalTrials.gov |
| Interventions | Training intervention + Dance intervention | ClinicalTrials.gov |
| First posted | 2019-10-29 | ClinicalTrials.gov |
| Last updated | 2020-06-01 | ClinicalTrials.gov |
Registered outcomes 45
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | the Coordination test | Day 1 | Participant is seated with legs strapped in to the mounts and moves legs to the beat of a metronome to assess central motor control. | ClinicalTrials.gov |
| Primary | TST (Triple Stimulation Technique) | day 3 | Technique in which nerves are stimulated to check guidance in the central nervous system | ClinicalTrials.gov |
| Primary | TMS (Transcranial Magnetic Stimulation) | Day 3 | Technique in which nerves are stimulated to check guidance in the central nervous system | ClinicalTrials.gov |
| Primary | the Voluntary Drive test | Day 1 | The participant is seated in a Biodex. While performing a leg extension the Quadriceps muscle is stimulated to check the guidance of electrical signals to the muscles. | ClinicalTrials.gov |
| Primary | the Fatigability Index Legs | Day 1 | Participant is seated in a Biodex and a protocol is performed to establish the muscle strength and muscle endurance of the legs. | ClinicalTrials.gov |
| Primary | Analysis of a Muscle Biopsy | Day 3 | A small piece of muscle tissue of the weakest leg will be biopsied and analyzed in the lab. | ClinicalTrials.gov |
| Primary | the Digit Span | Baseline | Cognitive test where numbers must be recalled in a certain order to evaluate short term memory | ClinicalTrials.gov |
| Primary | the Digit Span | Week 11 | Cognitive test where numbers must be recalled in a certain order to evaluate short term memory | ClinicalTrials.gov |
| Primary | the Stroop test | Baseline | Cognitive test to evaluate attention and simultaneous processing of multiple stimuli. | ClinicalTrials.gov |
| Primary | the Stroop test | week 11 | Cognitive test to evaluate attention and simultaneous processing of multiple stimuli. | ClinicalTrials.gov |
| Primary | the Paced Auditory Serial Addition Test (PASAT) | Baseline | This is a cognitive test where the participant will try to retain certain numbers they hear and do math. Correct answer last 1/3 vs first 1/3 | ClinicalTrials.gov |
| Primary | the Paced Auditory Serial Addition Test (PASAT) | Week 11 | This is a cognitive test where the participant will try to retain certain numbers they hear and do math. Correct answer last 1/3 vs first 1/3 | ClinicalTrials.gov |
| Primary | the Symbol Digit Modality Test (SDMT) (Cognitive fatigability) | Baseline | his is a cognitive performance test, substantiated with focus, speed, and visual scanning. Correct answers last 30 seconds vs first 30 seconds | ClinicalTrials.gov |
| Primary | the Symbol Digit Modality Test (SDMT) (Cognitive fatigability) | week 11 | his is a cognitive performance test, substantiated with focus, speed, and visual scanning. Correct answers last 30 seconds vs first 30 seconds | ClinicalTrials.gov |
| Primary | Motor function test (lower limb muscle strength) | Baseline | This is a motor test to assess the functional lower limb muscle strength. The participant is asked to stand from a seated position and sit down again as fast as possible for five times in a row. | ClinicalTrials.gov |
| Primary | Motor function test (lower limb muscle strength) | week 11 | This is a motor test to assess the functional lower limb muscle strength. The participant is asked to stand from a seated position and sit down again as fast as possible for five times in a row. | ClinicalTrials.gov |
| Primary | 25 Foot Walk (T25FW) test | Baseline | his is a motor test at which the participant is instructed to walk 25 ft (=7,62 meter) as fast and safely as possible. This is a quantitative performance test to assess mobility and leg function. | ClinicalTrials.gov |
| Primary | 25 Foot Walk (T25FW) test | week 11 | his is a motor test at which the participant is instructed to walk 25 ft (=7,62 meter) as fast and safely as possible. This is a quantitative performance test to assess mobility and leg function. | ClinicalTrials.gov |
| Primary | Nine Hole Peg Test (NHPT) | Baseline | This is a motor test to assess the participant's manual skills. This test records the time the participant needs to place 9 pins in the pegboard and remove them again. | ClinicalTrials.gov |
| Primary | Nine Hole Peg Test (NHPT) | week 11 | This is a motor test to assess the participant's manual skills. This test records the time the participant needs to place 9 pins in the pegboard and remove them again. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 34744669 | DERIVED | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Digit Span Test | Primary outcome | ConductCognition |
| Paced Visual Serial Addition Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)