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Trial · NCT04155918

Registered outcomes24

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPD profile of AR882 administered alone or in combination with febuxostat22 DaysProfile from serum uric acid concentration over time
PrimaryPD profile of AR882 administered alone or in combination with allopurinol22 DaysProfile from serum uric acid concentration over time.
PrimarySerum uric acid (sUA) response rate22 DayssUA response rate to achieve sUA \<6, \<5, \<4, and \<3 mg/dL
SecondaryArea under the curve (AUC) for plasma AR88222 DaysProfile from plasma in terms of AUC for AR882
SecondaryTime to maximum plasma concentration (Tmax) for AR88222 DaysProfile from plasma in terms of Tmax for AR882
SecondaryMaximum plasma concentration (Cmax) for AR88222 DaysProfile from plasma in terms of Cmax for AR882
SecondaryApparent terminal half-life (t1/2) for AR88222 DaysProfile from plasma in terms of t1/2 for AR882
SecondaryAmount excreted (Ae) into urine for AR88222 DaysProfile from urine in terms of Ae for AR882
SecondaryRenal clearance (CLr) for AR88222 DaysProfile from urine in terms of CLr for AR882
SecondaryAUC for plasma for febuxostat22 DaysProfile from plasma in terms of AUC for febuxostat
SecondaryTmax for febuxostat22 DaysProfile from plasma in terms of Tmax for febuxostat
SecondaryCmax for febuxostat22 DaysProfile from plasma in terms of Cmax for febuxostat
Secondaryt1/2 for febuxostat22 DaysProfile from plasma in terms of t1/2 for febuxostat
SecondaryAUC for plasma allopurinol/oxypurinol22 DaysProfile from plasma in terms of AUC for allopurinol/oxypurinol
SecondaryTmax for allopurinol/oxypurinol22 DaysProfile from plasma in terms of Tmax for allopurinol/oxypurinol
SecondaryCmax for allopurinol/oxypurinol22 DaysProfile from plasma in terms of Cmax for allopurinol/oxypurinol
Secondaryt1/2 for for allopurinol/oxypurinol22 DaysProfile from plasma in terms of t1/2 for allopurinol/oxypurinol
SecondaryAe in urine for allopurinol/oxypurinol22 DaysProfile from urine in terms of Ae for allopurinol/oxypurinol
SecondaryCLr for allopurinol/oxypurinol22 DaysProfile from urine in terms of CLr for allopurinol/oxypurinol
SecondaryAUC for plasma for colchicine22 DaysProfile from plasma in terms of AUC for colchicine

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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