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Trial · NCT04157335

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Endoscopic Total Nasal Polyp Score (NPS) at Week 56Double Blind Benralizumab-0.3Standard Deviation 1.6Score
Change From Baseline in Endoscopic Total Nasal Polyp Score (NPS) at Week 56Double Blind Placebo-0.1Standard Deviation 1.3Score
Change From Baseline in Mean Nasal Blockage Score (NBS) at Week 56.Double Blind Benralizumab-0.64Standard Deviation 0.98Score
Change From Baseline in Mean Nasal Blockage Score (NBS) at Week 56.Double Blind Placebo-0.45Standard Deviation 0.90Score
Change From Baseline in Difficulty With Sense of Smell (DSS) Score at Week 56.Double Blind Benralizumab-0.26Standard Deviation 0.78Score
Change From Baseline in Difficulty With Sense of Smell (DSS) Score at Week 56.Double Blind Placebo-0.05Standard Deviation 0.56Score
Sinus Opacification by CT Scan at Week 56.Double Blind Benralizumab-1.3Standard Deviation 3.4Score
Sinus Opacification by CT Scan at Week 56.Double Blind Placebo-0.7Standard Deviation 3.5Score
Disease Specific Health-related Quality of Life (HRQoL): Change From Baseline in SinoNasal Outcome Test (SNOT-22) Score at Week 56.Double Blind Benralizumab-18.0Standard Error 29.6Score
Disease Specific Health-related Quality of Life (HRQoL): Change From Baseline in SinoNasal Outcome Test (SNOT-22) Score at Week 56.Double Blind Placebo-15.2Standard Error 26.6Score
Time to First Nasal Polyp SurgeryDouble Blind Benralizumab6.31Full Range 3.3 to 10.5Months
Time to First Nasal Polyp SurgeryDouble Blind Placebo7.79Full Range 4.4 to 12.4Months
Time to First SCS Course for CRSwNPDouble Blind Benralizumab5.62Full Range 0.1 to 13.0Months
Time to First SCS Course for CRSwNPDouble Blind Placebo6.37Full Range 0.1 to 11.4Months
Time to First NP Surgery and/or SCS Use for CRSwNPDouble Blind Benralizumab5.70Full Range 0.1 to 13.0Months
Time to First NP Surgery and/or SCS Use for CRSwNPDouble Blind Placebo6.37Full Range 0.1 to 12.4Months
Change From Baseline in Bi-weekly Mean Nasal Polyps Symptom Diary Total Symptom Score at Week 56.Double Blind Benralizumab-3.19Standard Deviation 5.78Score
Change From Baseline in Bi-weekly Mean Nasal Polyps Symptom Diary Total Symptom Score at Week 56.Double Blind Placebo-2.32Standard Deviation 5.83Score
Percentage of Participants With Surgery and/or Use SCS for CRSwNPDouble Blind Benralizumab26Participants
Percentage of Participants With Surgery and/or Use SCS for CRSwNPDouble Blind Placebo30Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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