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Trial · NCT04173494

Results by group50

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Total Symptom Score (TSS) Response Rate at Week 24MMB 200 mg QD + Placebo24.6295% Confidence Interval 17.49 to 32.94Percentage of participants
Total Symptom Score (TSS) Response Rate at Week 24DAN 300 mg BID + Placebo9.2395% Confidence Interval 3.46 to 19.02Percentage of participants
Percentage of Participants With Transfusion Independence (TI) at Week 24MMB 200 mg QD + Placebo30.095% Confidence Interval 22.28 to 38.66Percentage of Participants
Percentage of Participants With Transfusion Independence (TI) at Week 24DAN 300 mg BID + Placebo20.0095% Confidence Interval 11.10 to 31.77Percentage of Participants
Splenic Response Rate (SRR) of >=25% at Week 24MMB 200 mg QD + Placebo39.2395% Confidence Interval 30.79 to 48.18Percentage of Participants
Splenic Response Rate (SRR) of >=25% at Week 24DAN 300 mg BID + Placebo6.1595% Confidence Interval 1.70 to 15.01Percentage of Participants
Change From Baseline in MFSAF TSS at Week 24MMB 200 mg QD + Placebo-9.36Standard Error 1.08Scores on a scale
Change From Baseline in MFSAF TSS at Week 24DAN 300 mg BID + Placebo-3.13Standard Error 1.62Scores on a scale
Splenic Response Rate (SRR) of >= 35% at Week 24MMB 200 mg QD + Placebo22.3195% Confidence Interval 15.48 to 30.44Percentage of Participants
Splenic Response Rate (SRR) of >= 35% at Week 24DAN 300 mg BID + Placebo3.0895% Confidence Interval 0.37 to 10.68Percentage of Participants
Percentage of Participants With Zero RBC Units Transfused Over 24-WeeksMMB 200 mg QD + Placebo35.3895% Confidence Interval 27.20 to 44.25Percentage of participants
Percentage of Participants With Zero RBC Units Transfused Over 24-WeeksDAN 300 mg BID + Placebo16.9295% Confidence Interval 8.76 to 28.27Percentage of participants
Percentage of Participants With <=4 RBC Units Transfused Over 24-weeksMMB 200 mg QD + Placebo55.3895% Confidence Interval 46.42 to 64.10Percentage of participants
Percentage of Participants With <=4 RBC Units Transfused Over 24-weeksDAN 300 mg BID + Placebo44.6295% Confidence Interval 32.27 to 57.47Percentage of participants
Duration of MFSAF TSS ResponseMMB 200 mg QD + Placebo286.00Inter-Quartile Range 286.00 to 286.00Days
Duration of MFSAF TSS ResponseDAN 300 mg BID + PlaceboNAInter-Quartile Range NA to NADays
Duration of TI ResponseMMB 200 mg QD + PlaceboNAInter-Quartile Range NA to NADays
Duration of TI ResponseDAN 300 mg BID + PlaceboNAInter-Quartile Range NA to NADays
Mean Cumulative Number of Whole Blood Units Transfused Over 24 WeeksMMB 200 mg QD + Placebo6.55Standard Deviation 8.413Whole blood units
Mean Cumulative Number of Whole Blood Units Transfused Over 24 WeeksDAN 300 mg BID + Placebo10.86Standard Deviation 13.203Whole blood units

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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